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Trafficking of antigens from gut to sacroiliac joints and spine in reactive arthritis and spondyloarthropathies: Mainly through lymphatics?
Joint Bone Spine
October 2016
Laboratoire d'investigation clinique (LIC) EA4393, université Paris Est-Créteil, 94010 Créteil, France; Service de rhumatologie, hôpital Henri-Mondor, AP-HP, 51, avenue Maréchal-de-Lattre-de-Tassigny, 94010 Créteil, France.
Bacterial trafficking from gut to mesenteric lymph nodes is physiologic only for a few commensal species, like Alcaligenes which produces antimicrobial-substances inhibiting growth of pathogenic bacteria. In reactive arthritis, some living bacteria transiently manage to travel from gut to joints/enthesis within dendritic cells and/or macrophages. Migration of dead or dormant bacteria outside the gut in spondyloarthropathies, including those associated with Crohn's disease, can occur either through blood or lymphatics.
View Article and Find Full Text PDF[Whipple's disease. Radiologic and clinical wrong interpretation as non-Hodgkin's lymphoma].
Rontgenpraxis
June 1992
I. Medizinische Klinik, Universität Heidelberg.
Whipple's disease may mimic clinically primary intestinal lymphoma. In addition, lymphographic findings in the paraaortic lymph nodes in Whipple's disease simulate malignant lymphoma. These severe tumor-like lymphographic changes are described in three cases of Whipple's disease.
View Article and Find Full Text PDFTissues obtained from 600 routine autopsies were studied. Mineral oil lipidosis was present in the spleen (76 per cent), liver (45 per cent), bone marrow (26 per cent), and lymph nodes; more than 50 per cent of the lymph nodes from the mesentery, porta hepatis, and mediastinum were affected. Mineral oil and its metabolic products produce a nonfibrogenic reaction in these tissues.
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