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Comparison of Papanicolaou Smear Tests Among HIV Negative and HIV Positive Pregnant Women on HAART at a Tertiary Hospital.
Niger Med J
January 2025
Department of Obstetrics and Gynaecology, Alex Ekwueme Federal University Teaching Hospital, Abakaliki, Nigeria.
Background: Cervical cancer is the most common gynaecological cancer worldwide, causing morbidity and mortality, especially in developing countries like Nigeria. It develops from premalignant lesions of the cervix. Human immune deficiency virus (HIV) increases the risk of dysplastic changes in the cervix.
View Article and Find Full Text PDFOptimizing UroVysion Fluorescence Hybridization Reflex Testing in Atypical Urothelial Cell Diagnosis: A Comprehensive Cytomorphological Analysis.
Ann Clin Lab Sci
November 2024
Department of Pathology and Translational Pathobiology, Louisiana State University Health Sciences Center, Shreveport, LA, USA
Objective: Urinary cytology is a key diagnostic tool for evaluating suspected urinary tract carcinoma, primarily high-grade urothelial carcinoma. The Paris System for Reporting Urinary Cytology (TPS), introduced in 2016, aimed to standardize reporting, though challenges with subjectivity and variability in diagnosing Atypical Urothelial Cells (AUCs) persist.
Methods: This retrospective study explored the correlation between cytomorphological features in "atypical" diagnosis and UroVysion fluorescence hybridization (U-FISH) results.
Performance of artificial intelligence for diagnosing cervical intraepithelial neoplasia and cervical cancer: a systematic review and meta-analysis.
EClinicalMedicine
February 2025
Department of Obstetrics and Gynecology, Affiliated Zhejiang Hospital, Zhejiang University School of Medicine, Hangzhou, 310013, China.
Background: Cervical cytology screening and colposcopy play crucial roles in cervical intraepithelial neoplasia (CIN) and cervical cancer prevention. Previous studies have provided evidence that artificial intelligence (AI) has remarkable diagnostic accuracy in these procedures. With this systematic review and meta-analysis, we aimed to examine the pooled accuracy, sensitivity, and specificity of AI-assisted cervical cytology screening and colposcopy for cervical intraepithelial neoplasia and cervical cancer screening.
View Article and Find Full Text PDFSerous Cystadenoma of the Pancreas: An Easily Missed Cytological Diagnosis and Clues to Diagnosis.
Diagn Cytopathol
January 2025
Department of Pathology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.
Serous cystadenoma (SCA) of the pancreas is a benign nonmucinous cystic pancreatic neoplasm and the second most common type of pancreatic cystic neoplasm. Conservative management is advocated in asymptomatic cases as they have indolent clinical behavior and risk for postoperative morbidity, making an exact diagnosis essential. Morphologically, serous cystadenoma has a prominent subepithelial capillary meshwork causing the aspirate to be paucicellular and nondiagnostic.
View Article and Find Full Text PDFAnaplastic large cell T-cell lymphoma: insights from cytological and immunological profiles across ten diverse cases.
Ann Biol Clin (Paris)
December 2024
Hematology Laboratory, Hospices Civils de Lyon, Centre Hospitalier Lyon Sud, Lyon, France.
While the latest WHO classification of hematological neoplasms helps refine the diagnostic criteria for anaplastic large cell lymphomas (ALCL), their diagnosis can still be challenging. This retrospective series of 10 ALCL cases illustrates the cytological appearance and immunological profile obtained through flow cytometry (FCM) from various sample types, including lymph node biopsies (LN), peripheral blood (PB), cerebrospinal fluid (CSF), and pleural fluid (PF). ALCL exhibits a polymorphic cytological appearance, ranging from "doughnut" cells to Hodgkin-like cells, very large cells, and small cells, with this polymorphism being particularly pronounced in ALK (-) forms.
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