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Antimicrobial and anti-biofilm effects of dihydroartemisinin-loaded chitosan nanoparticles against methicillin-resistant Staphylococcus aureus.
Microb Pathog
December 2024
School of Public Health, Southwest Medical University, Luzhou, China.
The formation of biofilms enhances bacterial antibiotic resistance, posing significant challenges to clinical treatment. Methicillin-resistant Staphylococcus aureus (MRSA) is a primary pathogen in biofilm-associated infections. Its high antibiotic resistance and incidence rates make it a major clinical challenge, underscoring the urgent need for novel therapeutic strategies.
View Article and Find Full Text PDFA clinical protocol for a German birth cohort study of the Maturation of Immunity Against respiratory viral Infections (MIAI).
Front Immunol
October 2024
Department of Pediatrics, University Hospital Würzburg, Würzburg, Germany.
Introduction: Respiratory viral infections (RVIs) are a major global contributor to morbidity and mortality. The susceptibility and outcome of RVIs are strongly age-dependent and show considerable inter-population differences, pointing to genetically and/or environmentally driven developmental variability. The factors determining the age-dependency and shaping the age-related changes of human anti-RVI immunity after birth are still elusive.
View Article and Find Full Text PDFAltered cingulate gyrus subregions functional connectivity in chronic insomnia disorder with anxiety.
Sleep Med
November 2024
Department of Neurology, Chengdu Second People's Hospital, The Affiliated Hospital of Chengdu Medical College, Chengdu, Sichuan, 610017, China. Electronic address:
Background: Chronic insomnia disorder (CID) is commonly associated with mood disorders. The cingulate gyrus (CG) plays a critical role in the pathophysiology of CID and anxiety. However, the specific characteristics of altered brain networks in the CG in CID with anxiety remain unclear.
View Article and Find Full Text PDFLacticaseibacillus rhamnosus CRL 2244 secreted metabolites display killing and antibiotic synergistic activity against multi-drug resistant pathogens.
PLoS One
June 2024
Center for Applied Biotechnology Studies, Department of Biological Science, College of Natural Sciences and Mathematics, California State University Fullerton (CSUF) Fullerton, CA, United States of America.
A growing increase in the number of serious infections caused by multidrug resistant bacteria (MDR) is challenging our society. Despite efforts to discover novel therapeutic options, few antibiotics targeting MDR have been approved by the Food and Drug Administration (FDA). Lactic acid bacteria have emerged as a promising therapeutic alternative due to their demonstrated ability to combat MDR pathogens in vitro.
View Article and Find Full Text PDFDeveloping a novel algorithm for comparing cluster patterns in networks on journal articles during and after COVID-19: Bibliometric analysis.
Medicine (Baltimore)
March 2024
Department of Pediatrics, Chi Mei Medical Center, Tainan, Taiwan.
Background: Cluster analysis is vital in bibliometrics for deciphering large sets of academic data. However, no prior research has employed a cluster-pattern algorithm to assess the similarities and differences between 2 clusters in networks. The study goals are 2-fold: to create a cluster-pattern comparison algorithm tailored for bibliometric analysis and to apply this algorithm in presenting clusters of countries, institutes, departments, authors (CIDA), and keywords on journal articles during and after COVID-19.
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