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PLoS One
January 2025
Division of Cell- and Neurobiology, Department of Biomedical and Clinical Sciences, Faculty of Medicine and Health Sciences, Linköping University, Linköping, Sweden.
Emerging evidence suggests that fusion of cancer cells with leucocytes, such as macrophages, plays a significant role in cancer metastasis and results in tumor hybrid cells that acquire resistance to chemo- and radiation therapy. However, the precise mechanisms behind the leukocyte-cancer cell fusion remain unclear. The present in vitro study explores the presence of fusion between the monocyte cell line (THP-1) and the breast cancer cell line (MCF-7) in relation to the expression of CD36 and phosphatidylserine with and without treatment of these cells with ionizing radiation.
View Article and Find Full Text PDFHeliyon
November 2024
Student Research Committee, Kermanshah University of Medical Sciences, Kermanshah, Iran.
This study conducted a systematic review and meta-analysis to explore the relationship between blood oxidative stress biomarkers and exposure to low-dose ionizing radiation in medical radiation workers. The researchers searched PubMed, Scopus, Web of Science, and Google Scholar for relevant studies until February 2023. They assessed the quality of the studies using the Newcastle‒Ottawa Scale (NOS) and used a random-effects model to combine the results.
View Article and Find Full Text PDFPhotodiagnosis Photodyn Ther
December 2024
Dept. of Urology, Research Laboratories, University of Leipzig, Liebigstraße 19, 04103 Leipzig, Germany. Electronic address:
Background: Photodynamic therapy (PDT) and radiotherapy using ionizing radiation (IR) are promising options for organ-preserving treatment of bladder cancer (BCa). A combination therapy (IR+PDT) could be beneficial for BCa treatment.
Purpose: For PDT, we used the near-infrared photosensitizer tetrahydroporphyrin-tetratosylate (THPTS) showing high therapeutic efficacy.
Int J Radiat Biol
January 2025
Department of Pharmaceutical Sciences, Beijing Institute of Radiation Medicine, Beijing, China.
Purpose: Ionizing radiation (IR) could induce damage such as DNA damage and oxidative stress. Natural products, like tea, have been demonstrated potential in mitigating these damages. However, the lack of efficient and rapid screening methods for natural products hinders their widespread application.
View Article and Find Full Text PDFActa Trop
December 2024
Department of Entomology, Aggeu Magalhães Institute/Oswaldo Cruz Foundation (IAM/Fiocruz), Recife, Pernambuco, Brazil.
This study characterizes the Aedes aegypti population from Fernando de Noronha Island, Pernambuco, Brazil, prior to implementing the Sterile Insect Technique (SIT). The main objective was to assess changes in glutathione S-transferase (GST) enzyme activity, previously linked to cypermethrin resistance in this population, in 2010. GST activity was measured in both male and female mosquitoes, masse produced in lab, after exposure to ionizing radiation.
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