A case is presented of what is believed to be the first reported instance of endometrioid-type cystadenocarcinoma discovered in a paraovarian cyst. The literature on paraovarian carcinomas is reviewed.
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Gynecol Oncol
March 2022
Foundation Medicine Inc., Cambridge, MA, United States of America.
Objectives: Endometrial serous carcinoma (EMSC) is an aggressive variant of uterine cancer with limited therapeutic options. We sought to define distinct clinicopathologic and genomic EMSC subgroups.
Methods: We retrospectively analyzed 2159 EMSC and 2346 endometrioid-type endometrial carcinomas (EEC) tissue specimens that had undergone comprehensive genomic profiling (CGP) via the FoundationOne CDx assay during routine clinical care.
J Cancer Res Ther
November 2021
Department of Pathology, Bankura Sammilani Medical College, Bankura, West Bengal, India.
Background: Ovarian cancer is the fifth common cause of death due to cancer in women. It constitutes 3% of all cancers in females and 15%-20% of genital malignancy. Most of the ovarian cancers are serous type followed by the endometrioid type.
View Article and Find Full Text PDFPathol Oncol Res
April 2020
Immunology Unit, Health Science University, Antalya Hospital, Antalya, Turkey.
Both uterine serous carcinoma (USC) and ovarian serous carcinoma (OSC) are presented at advanced stage at the first admittion and dissseminated disease makes the anatomical site of the tumor origin imposible. CA125 and p53 are reliable markers that are useful for differentiating both uterine serous and ovarian serous carcinoma from their most common subtypes (endometrioid type carcinoma of ovary and uterus) but so far there is no histopathologic marker that differentiates USC from OSC. On the other hand, Trastuzumab (Herceptin) increases progression-free survival among USC patients, but not OSC patients and makes the histopathologically assigning the origin of the tumor important.
View Article and Find Full Text PDFGynecol Oncol
July 2019
Gynecologic Oncology Unit, University of Bologna, Policlinico S.Orsola-Malpighi, Via Masserenti 13, 40138 Bologna, Italy.
Aim: Although obesity has been associated with endometrioid (type I) and, to a lesser extent, with serous (type II) endometrial cancer (EC), the association with the same histotypes of ovarian cancer (OC) remains unclear. Therefore, we intended to compare the role of BMI in carcinogenesis of endometrioid and the serous malignancies, at both ovarian and endometrial level.
Methods: A retrospective case-to-case study was performed in the University Hospital of Bologna (Italy), through the review of primary EC matched with the corresponding OC cases in the same period (1988-2017).
Asian Pac J Cancer Prev
May 2018
Department of Obstetrics and Gynecology, Prapokklao Hospital, Chanthaburi 22000, Thailand. Email:
Objective: To determine any association between the menopausal status and epithelial ovarian cancer coexisting with endometriosis (EOC-E). In addition, the prevalence and possible risk factors were assessed. Methods: Medical records of 172 women with epithelial ovarian cancer between January 2011 and December 2016 at Prapokklao Hospital were reviewed and divided into two groups: EOC-E defined as the case group and without endometriosis (EOC-NE) as the control group.
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