Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Antipolyphosphate monoclonal antibodies derived from autoimmune mice.
Res Pract Thromb Haemost
August 2024
Department of Biological Chemistry, University of Michigan Medical School, Ann Arbor, Michigan, USA.
Background: Inorganic polyphosphates (polyPs) are linear chains of phosphates that accelerate blood clotting. Targeting polyP has been shown to reduce thrombosis.
Objectives: To identify and characterize anti-polyP monoclonal antibodies that could be used as analytical tools and as antithrombotic agents.
Immune isolation-enabled nanoencapsulation of donor T cells: a promising strategy for mitigating GVHD and treating AML in preclinical models.
J Immunother Cancer
September 2024
Institute of Clinical Pharmacology, Anhui Medical University, Hefei, Anhui, China
Background: In allogeneic-hematopoietic stem cell transplantation for acute myeloid leukemia (AML), donor T cells combat leukemia through the graft-versus-leukemia (GVL) effect, while they also pose a risk of triggering life-threatening graft-versus-host disease (GVHD) by interacting with recipient cells. The onset of GVHD hinges on the interplay between donor T cells and recipient antigen-presenting cells (APCs), sparking T-cell activation. However, effective methods to balance GVHD and GVL are lacking.
View Article and Find Full Text PDFSynergistic nanocoating with layer-by-layer functionalized PCL membranes enhanced by manuka honey and essential oils for advanced wound healing.
Sci Rep
September 2024
School of Engineering, Newcastle University, Newcastle Upon Tyne, NE1 7RU, UK.
Chronic wounds represent a significant global health concern, statistically impacting 1-2% of the population in developed countries throughout their lifetimes. These wounds cause considerable discomfort for patients and necessitate substantial expenditures of time and resources for treatment. Among the emerging therapeutic approaches, medicated dressings incorporating bioactive molecules, including natural compounds, are particularly promising.
View Article and Find Full Text PDFAntibacterial properties of photo-crosslinked chitosan/methacrylated hyaluronic acid nanoparticles loaded with bacitracin.
Int J Biol Macromol
October 2024
3B's Research Group, I3Bs - Research Institute on Biomaterials, Biodegradables and Biomimetics, University of Minho, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, AvePark, Parque de Ciência e Tecnologia, Zona Industrial da Gandra, 4805-017 Barco, Guimarães, Portugal; ICVS/3B's-PT Government Associate Laboratory, Braga/Guimarães, Portugal. Electronic address:
The current treatments for wounds often fail to induce adequate healing, leaving wounds vulnerable to persistent infections and development of drug-resistant microbial biofilms. New natural-derived nanoparticles were studied to impair bacteria colonization and hinder the formation of biofilms in wounds. The nanoparticles were fabricated through polyelectrolyte complexation of chitosan (CS, polycation) and hyaluronic acid (HA, polyanion).
View Article and Find Full Text PDFCellulose derivatives as environmentally-friendly additives in water-based drilling fluids: A review.
Carbohydr Polym
October 2024
Department of Petroleum Engineering, NED University of Engineering & Technology, University Road, Karachi 75270, Pakistan.
Article Synopsis
- Cellulose derivatives like carboxymethyl cellulose (CMC) and cellulose nanomaterials (CNMs) are gaining popularity as eco-friendly additives in water-based drilling fluids (WBDFs) due to their biodegradable and biocompatible nature.
- CNMs, which include cellulose nanofibrils (CNFs) and cellulose nanocrystals (CNCs), offer unique properties such as a large surface area and enhanced mechanical performance, making them effective rheological modifiers and fluid loss reducers in drilling applications.
- The review discusses the structure, synthesis, and specific applications of these cellulose derivatives in WBDFs, while also addressing the challenges and future research directions for their effective use.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!