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[New systemic treatment approaches for conjunctival melanoma].
Ophthalmologie
March 2025
Zentrum für Augenheilkunde, Universitätsklinikum Köln, Köln, Deutschland.
Conjunctival melanoma is a rare disease that nevertheless has a high tumor-associated mortality rate. A resection in sano with adjuvant local treatment currently represents the therapeutic gold standard and systemic treatment is used for metastasized conjunctival melanoma and/or very advanced nonresectable local findings. New knowledge on molecular changes in conjunctival melanoma shows a clear similarity to those of cutaneous melanoma.
View Article and Find Full Text PDFSmartphone conjunctiva photography for malaria risk stratification in asymptomatic school age children.
NPJ Digit Med
March 2025
Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, USA.
Malaria remains a major global health challenge. Although effective control relies on testing all suspected cases, asymptomatic infections in school-age children are frequently overlooked. Advances in retinal imaging and computer vision have enhanced malaria detection.
View Article and Find Full Text PDFClinical profiles and treatment outcomes of 51 cases of carotid cavernous fistula: a retrospective observational study.
Korean J Ophthalmol
March 2025
Neuroophthalmology Division, Ophthalmology Department, Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo Hospital, Indonesia.
Purpose: This study investigated carotid-cavernous fistula (CCF) demographics, clinical profiles, imaging results, and treatment outcomes.
Methods: Our retrospective analysis included CCF patients' medical records from January 2016 to January 2022. This study included 51 cases-34 traumatic and 17 spontaneous CCFs.
Conjunctival Melanoma: A Narrative Review of Current Knowledge.
Pigment Cell Melanoma Res
March 2025
Faculty of Medicine, Department of Plastic Surgery, Aristotle University of Thessaloniki, Thessaloniki, Greece.
This review explores the current literature on conjunctival melanoma, a rare and complex periocular neoplasm, emphasizing the absence of a standardized treatment protocol and the associated management challenges. It examines the clinical, genetic, and histological features of conjunctival melanoma, alongside diagnostic methodologies and treatment strategies, drawing on the most recent bibliographic data. The literature was systematically reviewed using the PubMed database, offering insights into future research directions and highlighting innovative treatment approaches, particularly for advanced-stage disease.
View Article and Find Full Text PDFManagement of fracture and displacement of a previously successful bilateral transconjunctival ab-externo XEN gel stent: a case report.
BMC Ophthalmol
February 2025
Zhejiang University, Eye Center of Second Affiliated Hospital, School of Medicine, No. 1 Xihu Boulevard, 310009, Hangzhou, Zhejiang Province, China.
Background: The XEN45 Gel Stent (XGS) is an innovative, minimally invasive glaucoma surgery device, which is typically inserted via an ab-interno method, avoiding conjunctival dissection. With increasing experience, some surgeons have advocated for a transconjunctival ab-externo approach, with or without conjunctival dissection, for the delivery of XGS.
Case Presentation: A 33-year-old male patient with a history of primary open-angle glaucoma diagnosed three years ago presented to the clinic with the complaint of visual field loss.
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