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Dengue haemorrhagic fever (DHF) in pregnancy.
BMJ Case Rep
March 2025
Obstetrics and Genecology, SDM College of Medical Sciences and Hospital, Dharwad, India.
Dengue haemorrhagic fever (DHF) is a common tropical disease. An increasing frequency of dengue fever and DHF in pregnancy is being observed, with a rising incidence among adults. This case report describes the management of a woman in her early 30s, gravida 3, para 2, at 34 weeks of gestation, presenting with DHF and dengue shock syndrome, with a history of two previous caesarean sections.
View Article and Find Full Text PDFSoluble tumour necrosis factor receptor 1 predicts hospitalization in children and young adults with dengue virus infection in the Philippines.
Cytokine
March 2025
Department of Pediatrics, University of British Columbia, Vancouver, Canada. Electronic address:
Background: Dengue fever is a common cause of acute febrile illness in the tropics and requires hospitalization for intravenous (IV) fluid therapy in a minority of patients. Predicting which patients will progress to severe disease is challenging. Soluble tumour necrosis factor receptor 1 (sTNFR1) is associated with severe dengue and may have prognostic value.
View Article and Find Full Text PDFDevelopment of a multi-epitope vaccine candidate to combat SARS-CoV-2 and dengue virus co-infection through an immunoinformatic approach.
Front Immunol
March 2025
Division of Metabolomics, Proteomics & Imaging facility, Regional Medical Research Centre, Indian Council of Medical Research (ICMR), Dibrugarh, Assam, India.
Background: Although the SARS-CoV-2 and dengue viruses seriously endanger human health, there is presently no vaccine that can stop a person from contracting both viruses at the same time. In this study, four antigens from SARS-CoV-2 and dengue virus were tested for immunogenicity, antigenicity, allergenicity, and toxicity and chosen to predict dominant T- and B-cell epitopes.
Methods: For designing a multi-epitope vaccine, the sequences were retrieved, and using bioinformatics and immunoinformatics, the physicochemical and immunological properties, as well as secondary structures, of the vaccine were predicted and studied.
[Dengue fever vaccination Recommendations from the Société Francophone de Médecine Tropicale et de Santé Internationale for Metropolitan France and Overseas Territories].
Med Trop Sante Int
December 2024
Président de la SFMTSI, SFMTSI Société francophone de médecine tropicale et santé internationale (ancienne SPE), Hôpital Pitié-Salpêtrière, Pavillon Laveran, 47-83 Boulevard de l'Hôpital, 75651 Paris cedex 13, France.
Dengue fever is spreading rapidly around the world, affecting nearly half the world's population. Causes include urbanization, human mobility, climate change and the spread of mosquito vectors such as In 2023 and 2024, there was a marked increase in cases and deaths worldwide. In mainland France, the increase in imported cases has generated local transmissions.
View Article and Find Full Text PDFThe influence of fluid resuscitation strategy on outcomes from dengue shock syndrome: a review of the management of 691 children in 7 Southeast Asian hospitals.
BMJ Glob Health
March 2025
Nuffield Department of Medicine, University of Oxford, Oxford, UK.
Introduction: The pathognomonic feature of dengue shock syndrome (DSS) is a transient capillary leak syndrome resulting in profound intravascular volume depletion. WHO management guidelines recommend particular parenteral fluid regimens during the critical leakage phase, including synthetic colloid solutions in certain circumstances. We set out to describe the actual fluid management strategies employed in different settings and to investigate relationships with clinical outcomes.
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