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Article Synopsis
  • The review highlights the significance of assessing body composition during pregnancy and its impact on maternal and fetal health, emphasizing the need for accurate evaluation methods.
  • Anthropometric measurements, such as body weight and skinfold thickness, are reliable, cost-effective tools for assessing maternal nutritional status and predicting potential pregnancy complications.
  • Various laboratory methods, including bioelectrical impedance analysis and ultrasound, complement anthropometric measurements in estimating body composition and facilitating early diagnosis of issues during pregnancy.
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Association between psoas muscle mass index and bone mineral density in patients undergoing hemodialysis.

Sci Rep

January 2025

Division of Nephrology, First Department of Integrated Medicine, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma-cho, Omiya-ku, Saitama City, 330-8503, Saitama, Japan.

Patients undergoing dialysis are at risk of osteoporosis and sarcopenia because of mineral and bone disorders or malnutrition. Additionally, maintaining muscle mass is important to prevent osteoporosis. The psoas muscle mass index (PMI) was recently used to evaluate muscle mass.

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Association of trabecular bone score corrected for tissue thickness with glucose metabolism in acromegaly.

Front Endocrinol (Lausanne)

December 2024

5th Department of Internal Medicine, Comenius University Faculty of Medicine, University Hospital Bratislava, Bratislava, Slovakia.

Introduction: Acromegaly is associated with increased vertebral fracture (VF) risk regardless of bone mineral density (BMD). However, the vertebral trabecular compartment is still low; a possible contributor to this may be impaired glucose metabolism (GM) which frequently complicates acromegaly. Additionally, soft tissue thickness may confound bone imaging in acromegaly patients.

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Purpose: To present the clinical, topographic, and densitometry outcomes of patients with corneal fibrosis treated with topical losartan.

Methods: In this case series, patients with corneal scars treated with topical losartan 0.8 mg/mL 4 times a day for 6 months were included.

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Alpha-1 antitrypsin deficiency (AATD) is a relatively rare genetic disorder, inherited in an autosomal codominant manner, that results in reduced serum AAT concentrations, with a consequent reduction in antielastase activity in the lungs, as well as an increased risk of diseases such as pulmonary emphysema, liver cirrhosis, and necrotizing panniculitis. It results from different mutations in the SERPINA1 gene, leading to changes in the AAT glycoprotein, which can alter its concentration, conformation, and function. Unfortunately, underdiagnosis is quite common; it is possible that only 10% of cases are diagnosed.

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