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The postgenomic era: implications for the clinical laboratory.
Arch Pathol Lab Med
March 2002
Department of Clinical Pathology, William Beaumont Hospital, Royal Oak, MI 48073-6769, USA.
Objectives: To review the advances in clinically useful molecular biological techniques and to identify their applications in clinical practice, as presented at the Tenth Annual William Beaumont Hospital DNA Symposium.
Data Sources: The 11 manuscripts submitted were reviewed and their major findings were compared with literature on the same topic.
Study Selection: Manuscripts address creative thinking techniques applied to DNA discovery, extraction of DNA from clotted blood, the relationship of mitochondrial dysfunction in neurodegenerative disorders, and molecular methods to identify human lymphocyte antigen class I and class II loci.
Environmental tobacco smoke: experimental facts and societal issues.
Fundam Appl Toxicol
January 1995
Institute of Toxicology and Environmental Health, University of California, Davis 95616.
Involuntary exposure to environmental tobacco smoke (ETS) in public or in working places is considered to be a serious risk to human health. This symposium addressed several issues of toxicological interest that are associated with exposure to ETS. Epidemiologic evidence obtained in human studies suggests that "passive smoking" increases the risk of developing lung cancer in nonsmokers and favors the development of respiratory tract infections in children.
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