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Radical Laparoscopic Pericystectomy of a Giant Hepatic Hydatid Cyst.
Cureus
October 2024
Department of Hepatobiliary Surgery, Pontificia Universidad Católica de Chile, Santiago, CHL.
Hydatidosis is an endemic zoonotic disease with an uneven geographical distribution due to the varying abundance of its intermediate hosts, primarily cattle, and sheep in different regions, leading to a higher concentration of cases in livestock areas. Despite advancements in medical treatment and interventional radiology, surgery remains the treatment of choice for patients with hepatic hydatid cysts (HHC). Over the past decade, laparoscopic management of HHC has gained popularity; however, controversies persist regarding optimal patient selection, surgical techniques, and follow-up protocols.
View Article and Find Full Text PDFOptimal endoscopic treatment and partial cystectomy with or without bladder augmentation for Hunner-type interstitial cystitis.
Low Urin Tract Symptoms
November 2023
Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Interstitial cystitis/bladder pain syndrome (IC/BPS) presents a significant challenge for urologists in terms of management, owing to its chronic nature and adverse impact on patient quality of life. Given the potential distinction between two disease entities within IC/BPS, namely Hunner-type IC and BPS without Hunner lesion, there is a need for an optimal therapeutic approach that focuses on the bladder lesions in Hunner-type IC. In cases where Hunner lesions are observed, complete transurethral ablation of these lesions should be prioritized as the initial intervention, as it has demonstrated effectiveness in symptom control.
View Article and Find Full Text PDFSpontaneous urinary bladder regeneration after subtotal cystectomy increases YAP/WWTR1 signaling and downstream BDNF expression: Implications for smooth muscle injury responses.
PLoS One
July 2023
Developmental and Stem Cell Biology, Research Institute, Hospital for Sick Children, Toronto, Ontario, Canada.
Article Synopsis
- Rodents can heal their bladders naturally after surgery, and specific proteins like YAP/WWTR1 and BDNF help this healing process.
- Researchers studied how these proteins affect bladder muscle cells during injury recovery, using rats as models to observe cell movement.
- The study found that when bladder cells were injured, certain signals increased cell movement and healing, but blocking these signals slowed down the recovery.
A case of rare metachronous four primary carcinoma.
J Cancer Res Clin Oncol
August 2023
Department of General Surgery, The Second Medical Center and National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100853, China.
Purpose: When more than two tumors are diagnosed in the same person, it is called multiple primary cancer. It is rare to be diagnosed as four primary cancers. Here, we present one elderly male patient suffered from testicular seminoma, gastric cancer, bladder cancer and breast cancer from 1946 to 2019.
View Article and Find Full Text PDFLaparoscopic Treatment Strategies for Liver Echinococcosis.
Infect Dis Ther
August 2022
Department of General Surgery, The General Hospital of Western Theater command, Chengdu, 610083, People's Republic of China.
Liver echinococcosis is clinically mainly composed of hepatic cystic echinococcosis (CE) and hepatic alveolar echinococcosis (AE). At present, laparoscopy has been comprehensively applied in the treatment of two types of liver echinococcosis. For hepatic CE treatment, both laparoscopic total pericystectomy and laparoscopic hepatectomy can achieve radical results, but the former is considered the first choice owing to its being more minimally invasive; laparoscopic subtotal pericystectomy and laparoscopic partial pericystectomy can be accepted as complementary options, considering the presence of complicated cysts and the level of laparoscopic technique in remote hospitals; laparoscopic cystectomy is simple, but it is not currently recommended for treatment of hepatic CE owing to poor efficacy and high risk of postoperative complications.
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