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Expanded Uses of the Dorsal Nasal Flap: Redefining the Nasal Reconstruction Algorithm.

Plast Reconstr Surg Glob Open

January 2025

From the Department of Plastic and Reconstructive Surgery, Lahey Hospital and Medical Center, Burlington, MA.

Background: Defects of the nose present complex reconstructive challenges to the plastic surgeon. We present our experience with using the dorsal nasal flap (DNF) to provide a durable reconstruction even in sizable defects that would otherwise be considered necessitating a paramedian forehead flap.

Methods: We conducted a retrospective chart review of patients who underwent reconstruction by DNF following resection of skin cancers on the nose.

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Some microbes in the rumen form 10,12 (10,12)-conjugated linoleic acid (CLA), a fatty acid that depresses synthesis of milk fat in dairy cattle and other lactating animals. Despite their importance to milk fat depression, the microbes responsible have been difficult to identify, and no laboratory strain is currently available for study. Here we describe the isolation of AP1, a bacterium that forms 10,12-CLA at fast rates.

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Background: Fish venoms have been poorly characterized and the available information about their composition suggests they are uncomplicated secretions that, combined with epidermal mucus, could induce an inflammatory reaction, excruciating pain, and, in some cases, local tissue injuries.

Methods: In this study, we characterized the 24-hour histopathological effects of lionfish venom in a mouse experimental model by testing the main fractions obtained by size exclusion-HPLC. By partial proteomics analysis, we also correlated these effects with the presence of some potentially toxic venom components.

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Pilomatrixoma, also called Malherbe's calcifying epithelioma or pilomatrixoma, is a benign adnexal tumor that originates from keratinocytes (cells of the hair matrix, the internal sheath of the hair root or the cortex) and constitutes the second most prevalent skin neoplasm in children. These lesions are typically slow-growing, firm, nodules located on the head, neck, trunk, and extremities (in decreasing order of frequency). Due to the rarity, combined with their varied clinical presentations, pilomatrixomas are often misdiagnosed.

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Rhinoplasty is one of the most common cosmetic procedures performed by plastic surgeons and otolaryngologists. Previous studies have concluded that the readability of rhinoplasty information does not meet the recommended guidelines for the 8th grade reading level. In this study, we performed an updated readability analysis and a comprehensive online review of decision-making factors for patients considering rhinoplasty.

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