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Purpose: To compare remineralisation efficacy between silver diamine fluoride (SDF) combined with potassium iodide (KI) and sodium fluoride (NaF) varnish using hydroxyapatite (HAP) artificial white spot lesions (AWSLs) demineralisation model.
Materials And Methods: A total of 25 HAP disks was randomly divided into five groups (n = 5): baseline, AWSLs, deionized water (DW), SDF-KI or F-varnish. After AWSLs were developed, the specimen was treated with either deionized water, SDF-KI or F-varnish.
Anterior chamber morphological and refractive outcomes following phacoemulsification in pseudoexfoliative eyes: A case-control study.
Eur J Ophthalmol
January 2025
Ophthalmology Department, ULS São José, Lisboa, Portugal.
Purpose: To compare changes in angle morphology, anterior chamber depth (ACD) and refractive prediction error (PE) after phacoemulsification between pseudoexfoliative (PEX) and non-PEX eyes.
Methods: Prospective case-control study of eyes submitted to cataract surgery. Biometric data and angle parameters - Anterior Chamber Angle (ACA), Angle Opening Distance (AOD), Scleral Spur Angles (SSA) and Trabecular Iris Space Area (TISA) - were measured preoperatively and 1-month postoperatively through swept-source anterior segment optical coherence tomography.
The effect of physical cues on platelet storage lesion.
Hematology
December 2025
Department of Blood Transfusion, First Affiliated Hospital, Third Military Medical University (Army Medical University), Chongqing, People's Republic of China.
Background: Platelet concentrates play an important role in clinical treatment such as platelet function disorders and thrombocytopenia. In the process of preparation and storage of platelets, centrifugation, leukofiltration, and agitation will cause morphological changes and impaired function of platelets, which is associated with the increase of platelet transfusion refractoriness, and named as platelet storage lesion (PSL).
Method: This paper proposes three major operations (centrifugation, agitation, and leukofiltration) that platelets experience during the preparation and storage process, to explore the effect of physical cues on PSL.
A new perspective on apoptosis: Its impact on meat and organoleptic quality in different animals.
Food Chem X
January 2025
Division of Food Technology & Nutrition, Sunmoon University, Asan-si 31460, South Korea.
Apoptosis serves as the initial phase in the conversion of muscle to meat, driving key biochemical and morphological changes in the postmortem muscle. To effectively improve and control meat quality across different animal species, it is important to gather more information on the mechanisms by which apoptotic potential, mediated through the interaction of apoptosis-related molecules, influences meat quality variations. The apoptotic potential, determined by the balance between apoptotic and anti-apoptotic molecules, such as Ca, cytochrome , caspases, and heat shock proteins, varies among different species.
View Article and Find Full Text PDFDopaminergic modulation of propofol-induced activation in VLPO neurons: the role of D1 receptors in sleep-promoting neural circuits.
Front Neurosci
January 2025
The Key Laboratory of Anesthesia and Organ Protection, The Key Laboratory of Brain Science, Zunyi Medical University, Zunyi, China.
Background: The ventrolateral preoptic nucleus (VLPO) is a crucial regulator of sleep, and its neurons are implicated in both sleep-wake regulation and anesthesia-induced loss of consciousness. Propofol (PRO), a widely used intravenous anesthetic, modulates the activity of VLPO neurons, but the underlying mechanisms, particularly the role of dopaminergic receptors, remain unclear.
Objective: This study aimed to investigate the effects of PRO on NA (-) neurons in the VLPO and to determine the involvement of D1 and D2 dopaminergic receptors in mediating these effects.
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