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[Long-term postoperative outcomes after surgical correction of congenital subaortic stenosis].
Khirurgiia (Mosk)
December 2024
Penza State University, Penza, Russia.
Objective: To analyze the results of surgical treatment of discrete subaortic stenosis and identify the main factors of left ventricular outflow tract (LVOT) restenosis in long-term postoperative period.
Material And Methods: There were 87 surgical interventions in 63 patients with congenital subaortic stenosis between 2008 and 2023. Mean preoperative peak systolic LVOT pressure gradient was 72 mmHg (50-110 mmHg).
Assessing subaortic right ventricle function after atrial switch repair through myocardial work analysis.
Int J Cardiol Congenit Heart Dis
December 2024
Division of Structural and Congenital Cardiology, University Hospitals Leuven, Leuven, Belgium.
Background: The Mustard and Senning operations for dextro-transposition of the great arteries (D-TGA) establish a biventricular physiology with a subaortic right ventricle (sRV). While prolonged QRS has been associated with worse prognosis in these patients, current echocardiographic tools fall short in adequately assessing the (mal)performance and function decline of the sRV during follow-up. The present study is the first to characterize Myocardial Work (MW) indices of the sRV in D-TGA patients after Mustard/Senning repair.
View Article and Find Full Text PDFA clinical perspective on surgical and diagnostic strategies for neonatal partial shone complex: Insights from a case report.
Int J Surg Case Rep
December 2024
The Internist Cardiologist, Department of Cardiology, Al Watani Hospital, Hama, Syria.
Article Synopsis
- Shone complex (SC) is a rare congenital heart disease involving four obstructive lesions in the left side of the heart, making up 0.6-0.7% of CHD cases.
- A 4-week-old male neonate with SC presented severe respiratory distress and related symptoms, leading to a diagnosis that included multiple heart issues and a successful surgical intervention at five months.
- Early detection through echocardiography and multidisciplinary care is crucial for effective management and improved patient outcomes in SC cases.
Contemporary Clinical Characteristics, Imaging, Management, and Surgical and Nonsurgical Outcomes of Adult Patients With Subaortic Stenosis.
J Am Heart Assoc
November 2024
Department of Cardiovascular Medicine Heart, Vascular and Thoracic Institute, Cleveland Clinic Cleveland OH USA.
Article Synopsis
- Subaortic stenosis (SAS) is a condition in adults where a fibromuscular membrane obstructs blood flow below the aortic valve, potentially leading to serious heart complications.
- A study of 484 patients between 2011 and 2022 showed that over a median follow-up of 5.5 years, 11.5% died, and 6.8% were hospitalized for heart failure, with notable recurrence of SAS in 8.0% of cases.
- Key factors impacting mortality and disease recurrence included older age and baseline heart function, highlighting the need for more research to improve treatment strategies.
Development of Novel 3D Spheroids for Discrete Subaortic Stenosis.
Cardiovasc Eng Technol
December 2024
Laboratory for Regenerative Tissue Repair, Texas Children's Hospital, Houston, TX, USA.
In this study, we propose a new method for bioprinting 3D Spheroids to study complex congenital heart disease known as discrete subaortic stenosis (DSS). The bioprinter allows us to manipulate the extrusion pressure to change the size of the spheroids, and the alginate porosity increases in size over time. The spheroids are composed of human umbilical vein endothelial cells (HUVECs), and we demonstrated that pressure and time during the bioprinting process can modulate the diameter of the spheroids.
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