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Polychlorinated biphenyls induced toxicities upon cell lines and stem cells: a review.
Environ Geochem Health
January 2025
School of Planning, Design and Construction, Michigan State University, East Lansing, MI, 48824, USA.
Polychlorinated biphenyls (PCBs) are persistent organic pollutants emitted during e-waste activities. Upon release into the environment, PCBs can pose harmful effects to the humans and environment. The present review focused on the effects of PCBs on cell proliferation, apoptosis, functional and developmental toxicity and potential possible molecular mechanisms upon cells and stem cells.
View Article and Find Full Text PDFDesign, Implementation and Environmental Impact of Cutoff Wall for Pollution Control in an Industrial Legacy Site.
Toxics
December 2024
Zhejiang Zone-King Environmental Sci & Tech Co., Ltd., Hangzhou 310064, China.
Heavy metal-organic pollutants compound pollution at industrial legacy sites and have caused damage to the ecological environment and human health during recent decades. In view of the difficulty and high cost of post-contamination remediation, it is worth studying, and practically applying, cutoff walls to reduce the spread of pollution in advance. In this study, field-scale studies were carried out at e-waste dismantling legacy sites in Taizhou, Zhejiang Province of China, through the process of site investigation, numerical simulation, and cutoff wall practical application.
View Article and Find Full Text PDFAssociations Between Prenatal Dioxin-like Polychlorinated Biphenyls Exposure and Glucocorticoid and Androgenic Hormones in Umbilical Cord Blood.
Environ Res
January 2025
Department of Laboratory Medicine, The First Affiliated Hospital of Zhengzhou University. Zhengzhou, Henan, China. Electronic address:
This study investigates the association between prenatal exposure to dioxin-like polychlorinated biphenyls (DL-PCBs) and glucocorticoid and androgenic hormone levels in cord blood. We analyzed cord blood samples from 500 mother-infant pairs from China (2022-2023), focusing on hormones including cortisol, cortisone, dehydroepiandrosterone (DHEA), and androstenedione. The main analysis revealed significant reductions in cortisol levels with increased exposure to PCB-77 (β = -3.
View Article and Find Full Text PDFThe mechanism of activity-controlled release of 2,2',4,4'-tetrabromodiphenyl degradation by polystyrene microcapsulated nanoscale zero-valent iron.
Environ Res
January 2025
School of Environment, South China Normal University, Guangzhou 510006, China; Guangdong T'echnology Research Center for Ecological Management and Remediation of Water System, Guangzhou 510006, china.
Nano zero-valent iron (nZVI) is widely used for polychlorinated biphenyl (PBDE) remediation due to its cost-effectiveness and strong reduction capacity. However, its practical application is limited by poor stability, mobility, and antioxidant performance, as well as high reactivity that leads to side reactions and activity loss. To overcome these challenges, a poly(styrene)-encapsulated nZVI (PS-nZVI) core-shell structure was developed using dispersion polymerization.
View Article and Find Full Text PDFPathophysiological Features of Remodeling in Vascular Diseases: Impact of Inhibitor of DNA-Binding/Differentiation-3 and Estrogenic Endocrine Disruptors.
Med Sci (Basel)
December 2024
Department of Health and Natural Sciences, Florida Memorial University, Miami Gardens, FL 33054, USA.
Vascular diseases, such as hypertension, atherosclerosis, cerebrovascular, and peripheral arterial diseases, present major clinical and public health challenges, largely due to their common underlying process: vascular remodeling. This process involves structural alterations in blood vessels, driven by a variety of molecular mechanisms. The inhibitor of DNA-binding/differentiation-3 (), a crucial member of ID family of transcriptional regulators, has been identified as a key player in vascular biology, significantly impacting the progression of these diseases.
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