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Background: Insufficient fluid administration intra- and postoperatively may lead to delayed renal graft function (DGF), while fluid overload increases the risk of heart failure, infection, and obstipation. Several different fluid protocols have been suggested to ensure optimal fluid state. However, there is a lack of evidence of the clinical impact of these regimens.

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[Side effects of pain therapy : Sufficient analgesia without unnecessary complications].

Urologe A

April 2017

Klinik für Anästhesiologie und Intensivtherapie, Universitätsklinikum Jena, Bachstraße 18, 07743, Jena, Deutschland.

Interventions of acute and chronic pain treatment are associated with risks. Therefore, it is important to know about treatment side effects in order to avoid unnecessary complications and therapy interruption. This knowledge, however, is not to prevent/abandon this treatment altogether.

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According to the German S3-guideline 'Palliative Medicine' which has been supported by the German Guideline Program in Oncology, constipation in palliative patients requires a consistent prophylaxis and therapy. Constipation is caused by immobilisation, poor health, exsiccosis, a low-fiber diet or a preexisting functional constipation. Further important causes are substances with constipating side effects, such as opioids or anticholinergic drugs.

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Proceedings of the 3rd IPLeiria's International Health Congress : Leiria, Portugal. 6-7 May 2016.

BMC Health Serv Res

July 2016

Faculdade de Ciências do Desporto e Educação Física, Universidade de Coimbra, 3040-248 Coimbra, Portugal

Article Synopsis
  • The text discusses various research studies focusing on health topics, including health literacy in adolescents and the impact of walking programs on individuals with schizophrenia.
  • It also covers innovative medical practices, safety culture in patient care, and the psychological effects experienced by emergency crews after disasters.
  • Additionally, it highlights issues such as musculoskeletal disorders in midwives, negative childhood experiences affecting adolescent mental health, and studies on vaccination timing and assessments in elderly care.
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Renal risk associated with sodium phosphate medication: safe in healthy individuals, potentially dangerous in others.

Expert Opin Drug Saf

July 2015

Charles University in Prague, 2nd Department of Internal Medicine, Third Faculty of Medicine , Ruská 87, 100 00 Prague 10 , Czech Republic +420 723 705 493, +420 267 162 703 ;

Introduction: Sodium phosphate purgatives are used for bowel preparation before endoscopic or radiologic examination and occasionally for treatment of severe obstipation. Generally, they are well tolerated and effective; however, safety concerns exist regarding serious renal injury and electrolyte disturbances after administration of these drugs.

Areas Covered: The review presents complications associated with the use of agents containing sodium phosphate with regard to electrolyte disorders and renal impairment, namely acute phosphate nephropathy (APhN).

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