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An Unusual Presentation of Cutaneous Bullous Lupus.
Cureus
November 2024
Rheumatology, Cooper University Health Care, Camden, USA.
Drug-induced lupus erythematosus (DILE) is an autoimmune reaction that results in symptoms of polyarthralgia, fever, and cutaneous lesions and other manifestations. Several drugs have been documented to cause this disease, including procainamide, isoniazid, methyldopa, penicillamine, and hydralazine. Systemic lupus erythematosus (SLE) manifestations often occur after the patient has been taking the drug without complications for months to years.
View Article and Find Full Text PDFGenetically Confirmed Wilson Disease: A Retrospective Cohort Study From Bahrain.
Cureus
October 2024
Department of Pediatrics, Salmaniya Medical Complex, Manama, BHR.
Introduction Wilson disease (WD) is a rare inherited autosomal recessive disorder caused by a mutation in the gene. This mutation affects copper metabolism, leading to the accumulation of copper in the liver, brain, cornea, and other tissues. If not treated, WD can lead to significant morbidities.
View Article and Find Full Text PDFIntoxication in a Colombian mercury mine: Aranzazu, 1948-1975.
Hist Cienc Saude Manguinhos
October 2024
Titular Professor, Escuela de Historia/Universidad Industrial de Santander. Bucaramanga - Colombia
Article Synopsis
- - The study examines the experiences of "La Esperanza" mercury mine workers in Aranzazu, Colombia, from 1948 to 1975, focusing on their occupational hazards and health issues.
- - Workers faced severe health risks due to unstable geological conditions and poor mining technology, leading to symptoms like tremors, bleeding gums, and bad breath.
- - This situation initiated the field of occupational toxicology in Colombia, as the mine was the first to provide treatment for mercury poisoning using dimercaprol and penicillamine.
Wilson's Disease in Childhood and the Challenges in Its Diagnosis: A Case Report.
Cureus
July 2024
Pediatrics, Sree Balaji Medical College and Hospital, Chennai, IND.
Wilson's disease is a genetic neurometabolic disorder affecting copper metabolism in the body. It occurs due to mutations in the ATP7B gene. Here, we report a case of a 12-year-old boy, born out of a second-degree consanguineous marriage, who presented with complaints of jaundice for the past one year, poor scholastic performance, and behavioral abnormalities for the past one month.
View Article and Find Full Text PDFSynthesis and Characterization of a Sustained Nitric Oxide-Releasing Orthodontic Elastomeric Chain for Antimicrobial Action.
Int J Mol Sci
June 2024
Department of Orthodontics, University of Louisville School of Dentistry, Louisville, KY 40202, USA.
The acidic byproducts of bacteria in plaque around orthodontic brackets contribute to white spot lesion (WSL) formation. Nitric oxide (NO) has antibacterial properties, hindering biofilm formation and inhibiting the growth of oral microbes. Materials that mimic NO release could prevent oral bacteria-related pathologies.
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