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Background: Cardiovascular disease remains the leading cause of mortality worldwide. Cardiac fibrosis impacts the underlying pathophysiology of many cardiovascular diseases by altering structural integrity and impairing electrical conduction. Identifying cardiac fibrosis is essential for the prognosis and management of cardiovascular disease; however, current diagnostic methods face challenges due to invasiveness, cost, and inaccessibility.

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Aims: To objectively characterize the spatial-velocity dynamics of the QRS-loop in the vectorcardiogram (VCG) of patients with acute myocardial infarction (AMI).

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Background: The Electrocardiogram (ECG) can be visualised either in a scalar form, as waves in the standard 12‑lead ECG, or vectorially, as vector loops in different planes in the Vectorcardiogram (VCG). An Electro-Vectorcardiogram (ECG-VCG) is a graphic visualization combining scalar and vector ECGs. We aimed to assess if integrating the scalar 12‑lead ECG and vector ECG makes ECG interpretation by medical students more accurate, faster, and easier than using 12‑lead ECG alone.

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Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.

Background: Manually derived electrocardiographic (ECG) parameters were not associated with mortality in mechanically ventilated COVID-19 patients in earlier studies, while increased high-sensitivity cardiac troponin-T (hs-cTnT) and N-terminal pro-B-type natriuretic peptide (NT-proBNP) were. To provide evidence for vectorcardiography (VCG) measures as potential cardiac monitoring tool, we investigated VCG trajectories during critical illness.

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