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Multimodal machine learning enables AI chatbot to diagnose ophthalmic diseases and provide high-quality medical responses.
NPJ Digit Med
January 2025
Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Chatbot-based multimodal AI holds promise for collecting medical histories and diagnosing ophthalmic diseases using textual and imaging data. This study developed and evaluated the ChatGPT-powered Intelligent Ophthalmic Multimodal Interactive Diagnostic System (IOMIDS) to enable patient self-diagnosis and self-triage. IOMIDS included a text model and three multimodal models (text + slit-lamp, text + smartphone, text + slit-lamp + smartphone).
View Article and Find Full Text PDFDose measurements with the Pille-ISS thermoluminescent dosimeter system during extravehicular activities (2004-2022).
Life Sci Space Res (Amst)
February 2025
Institute of Biomedical Problems of the Russian Academy of Sciences, 76A Khoroshevskoye shosse, 123007, Moscow, Russian Federation.
One of the most problematic goals for radiation safety during spaceflight is an assessment of additional doses received by astronauts during extravehicular activity (EVA). The Pille-ISS thermoluminescent dosimeter developed by the predecessor of the Hungarian Research Network (HUN-REN) Centre for Energy Research (Budapest, Hungary) is designed for the routine dose measurements not only inside the spacecraft compartments, but also for personal dosimetric control for EVA. During almost two decades of the International Space Station (ISS) operation, the unique set of 131 EVA doses were recorded in different conditions, such as: solar activity, ISS trajectory along the South Atlantic Anomaly (SAA), and shielding conditions provided by two kinds of spacesuits: the Extravehicular Mobility Unit (EMU) and Orlan.
View Article and Find Full Text PDFHybrid Carbohydrate-Lipid Nanocarriers: In Vitro Efficacy Gene-Rated by Association of UV-Absorbers and Raspberry Polyphenols Rich-Fraction.
Pharmaceuticals (Basel)
December 2024
Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology POLITEHNICA of Bucharest, Polizu No 1, 011061 Bucharest, Romania.
The study aims to investigate an improved version of lipid nanocarriers (NLCs) (formulated with functional coconut butter and marula oil) by designing hyaluronic acid (HA) decorated NLC co-loaded with dual UVA (butyl methoxy dibenzoyl methane, BMDBM), UVB absorbers (ethyl-hexyl-salicylate, EHS) and a Raspberry rich polyphenols fraction (RPRF) for development of more natural NLC-based to-pical formulations. : Quality and quantitative attributes of classic- and HA-NLC have been assigned based on particle size, electrokinetic potential, encapsulation efficiency, spectroscopic characteristics, and high-resolution mass spectrometry. To establish the performance profile of antioxidant activity, release of active substances, sun blocking action, and photostability, in vitro studies were conducted.
View Article and Find Full Text PDFLow-Dose Ionizing Radiation and Thyroid Diseases and Functional Modifications in Exposed Workers: A Systematic Review.
J Clin Med
January 2025
Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.
With technological development, ionizing radiation has found applications in numerous occupations. However, the determination and quantification of the damage resulting from exposure to it remains rather unclear, along with the damage to particular organs. The aim of this systematic review was to investigate the relationship between low-dose ionizing radiation (LDIR) in exposed workers and possible functional changes and cancer development in the thyroid gland.
View Article and Find Full Text PDFCharacterising Carbon Monoxide Household Exposure and Health Impacts in High- and Middle-Income Countries-A Rapid Literature Review, 2010-2024.
Int J Environ Res Public Health
January 2025
Environmental Epidemiology Team, Radiation, Chemical and Environmental Hazards Directorate, UK Health Security Agency (UKHSA), Didcot OX11 0RQ, UK.
Carbon monoxide (CO) is a toxic gas, and faulty gas appliances or solid fuel burning with incomplete combustion are possible CO sources in households. Evaluating household CO exposure models and measurement studies is key to understanding where CO exposures may result in adverse health outcomes. This assists the assessment of the burden of disease in high- and middle-income countries and informs public health interventions in higher-risk environments.
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