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Traumatic limb amputations in polytrauma ICU admissions.
S Afr J Surg
December 2024
Department of Surgical Sciences, Nelson R Mandela School of Clinical Medicine, University of KwaZulu-Natal, South Africa.
Background: KwaZulu-Natal bears a significant trauma burden, with polytrauma patients often experiencing traumatic limb amputations. This study investigates traumatic limb amputations in the subgroup of severely injured polytrauma patients admitted to the trauma ICU in KwaZulu-Natal. This study aims to describe the management and outcomes of traumatic limb amputations in polytrauma patients at the trauma ICU.
View Article and Find Full Text PDFMining of Meroterpenoids with Anti-inflammatory Activity from the Mangrove Endophytic Fungus sp. JNQQJ-4 by Genome Analysis and Molecular Network Strategy.
Org Lett
January 2025
School of Pharmacy, Anhui Medical University, Hefei 230032, China.
Talaromeroterpenoids A-G (-), seven new 3,5-dimethylorsellinic-acid-derived meroterpenoids, and two known analogues ( and ) were isolated from the mangrove endophytic fungus sp. JNQQJ-4 by genome analysis and a molecular networking strategy. Their structures and absolute configurations were established by nuclear magnetic resonance data, high-resolution electrospray ionization mass spectrometry, and X-ray diffraction.
View Article and Find Full Text PDFIntroduction: Chronic ischemic heart failure is a major global health issue despite advancements in therapy. Stem cell (SC) therapy has emerged as a potential treatment, but its effectiveness remains uncertain. This study aimed to systematically review and meta-analyze the current evidence on SC therapy's efficacy.
View Article and Find Full Text PDFDeconvoluting thermomechanical effects in X-ray diffraction data using machine learning.
Acta Crystallogr A Found Adv
March 2025
Pennsylvania State University, University Park, PA 16802, USA.
X-ray diffraction is ideal for probing the sub-surface state during complex or rapid thermomechanical loading of crystalline materials. However, challenges arise as the size of diffraction volumes increases due to spatial broadening and because of the inability to deconvolute the effects of different lattice deformation mechanisms. Here, we present a novel approach that uses combinations of physics-based modeling and machine learning to deconvolve thermal and mechanical elastic strains for diffraction data analysis.
View Article and Find Full Text PDFDietary Modification Patterns and Interventions Among Weight Loss Seekers in Tamil Nadu, South India: A Cross-Sectional Analysis of Intermittent Fasting and Alternative Dietary Approaches.
Cureus
December 2024
Community Medicine, Dhanalakshmi Srinivasan Medical College and Hospital, Siruvachur, IND.
Background The escalating global obesity epidemic requires comprehensive investigations for effective weight management strategies. Understanding the patterns, barriers, and facilitators of dietary interventions is crucial for developing effective weight management protocols. This research aims to assess dietary modification interventions among weight loss subjects in Tamilnadu, South India.
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