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The Value of Lacrimal Gland Ultrasonography and Shear Wave Elastography in the Evaluation of Primary Sjögren's Syndrome: A Cross-Sectional Study.
J Clin Ultrasound
January 2025
Department of Ultrasonography, The Second Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Purpose: This study evaluates the effectiveness of lacrimal gland ultrasonography (LGUS) and shear wave elastography (SWE) in distinguishing primary Sjögren's syndrome (PSS) patients from healthy controls and examines their role in assessing disease activity and prognosis.
Methods: A total of 35 PSS patients and 23 age- and gender-matched healthy controls were included. LGUS was used to grade lacrimal gland structure, while SWE assessed gland elasticity.
Risk Factors for Viral Coinfections in Blood Donors in Bahia, Brazil.
J Med Virol
February 2025
Programa de Pós-Graduação em Medicina e Saúde, Universidade Federal da Bahia, Salvador, Brazil.
Human Immunodeficiency Virus (HIV), Human T Lymphotropic Virus (HTLV), Hepatitis B Virus (HBV) and Hepatitis C Virus (HCV) coinfection may lead to disease progression or worsen its clinical presentation. Viral coinfections screening during blood donation is critical. To identify risk factors for coinfection among blood donors, we assessed the blood donations at the Fundação de Hematologia e Hemoterapia da Bahia, from 2008 to 2017.
View Article and Find Full Text PDFAn observational study to determine the role of indirect immunofluorescence and ELISA for desmogleins in the diagnosis and monitoring of autoimmune bullous disorders.
Med J Armed Forces India
August 2022
Professor & Head (Dermatology), DY Patil Medical College & Research Centre, Pune, India.
Background: Autoimmune bullous disorder (AIBD) is a diverse group of blistering dermatoses that affects the skin and mucous membrane, characterized by the formation of autoantibodies against the desmosomal glycoproteins and adhesion molecular components of the basement membrane zone. Various immunoassay techniques for serological diagnosis are Direct Immunofluorescence (DIF), Indirect Immunofluorescence (IIF), Enzyme Linked Immunosorbent Assay (ELISA) and immunoblotting. Quantitative ELISA titer can also be used to monitor the disease activity and response to treatment.
View Article and Find Full Text PDFImmune Profile Differences between IgG4-Related Diseases and Primary Sjögren's Syndrome.
J Inflamm Res
January 2025
Department of Rheumatology, The Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, People's Republic of China.
Purpose: Immunoglobulin G4-related disease (IgG4-RD) share clinical features with primary Sjögren's syndrome (pSS). This study aimed to identify altered serological parameters and potential biomarkers of IgG4-RD and pSS.
Methods: Forty IgG4-RD patients, 40 pSS patients, and 40 healthy controls (HC) were enrolled in this study.
Seroprevalence of dengue, Zika, and chikungunya in São Sebastião, Brazil (2020-2021): a population-based survey.
BMC Infect Dis
January 2025
Interdisciplinary Laboratory of Biosciences, Faculty of Medicine, University of Brasília, Federal District, Brasília, Brazil.
Background: Urban arboviruses pose a significant global burden, particularly in tropical regions like Brazil. São Sebastião, a lower-middle-class urban area just 26 km from the Brazilian capital, is an endemic area for dengue. However, asymptomatic cases may obscure the actual extent of the disease.
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