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Objective: To evaluate the pathologic ocular changes in a population of aquarium-housed Monodactylus argenteus and investigate potential underlying causes for the large number of affected fish in this exhibit.

Animals: 11 Monodactylus argenteus were evaluated from a shoaling ring exhibit within an aquarium, and 19 control fish without ocular abnormalities were obtained from commercial fish suppliers.

Methods: Physical and ocular examinations were performed antemortem.

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Article Synopsis
  • Iris nodules are common in neurofibromatosis type 1, but other eye issues are rare; this study highlights a patient with a phthisic eye who had it removed for cosmetic reasons after 15 years.
  • The case focuses on a 17-year-old male who underwent multiple surgeries due to complications, including total retinal detachment, with the enucleated eye showing signs of massive retinal gliosis and no apparent neurofibromas in some areas.
  • A review of 14 similar cases revealed a pattern of eye conditions like glaucoma and neurofibromas in certain structures, indicating various ocular manifestations of neurofibromatosis type 1.
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Progression to bilaterality in unilateral primary congenital glaucoma.

J AAPOS

August 2024

Dr Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. Electronic address:

Purpose: To evaluate the incidence of rise in intraocular pressure (IOP) in fellow eyes of patients with unilateral primary congenital glaucoma (PCG) and to identify risk factors for IOP increase over long-term follow-up.

Methods: The medical records of unilateral PCG patients who had completed at least 5 years of follow-up were reviewed retrospectively. The incidence of developing ocular hypertension / glaucoma in fellow eyes was analyzed.

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Purpose: To study the fellow eyes of patients with unilateral primary congenital glaucoma (PCG) using optical coherence tomography angiography (OCTA) and compare them to normal age- and refractive error-matched healthy controls.

Methods: Using OCTA, the foveal avascular zone (FAZ) area, cup:disk ratio, vessel density (VD) of the optic nerve head (ONH) and peripapillary area and the macular VD in superficial (SCP) and deep vascular complexes in both 3 mm and 6 mm scans of both groups were compared. Clinical data included best-corrected visual acuity (BCVA), cycloplegic refraction, intraocular pressure (IOP), anterior and posterior segments examination findings, including ONH cup:disk ratio.

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Unilateral buphthalmos, corneal staphyloma and corneal fistula caused by pathogenic variant in the PITX3 gene: a case report.

BMC Ophthalmol

September 2022

Department of ophthalmology, West China Hospital, Sichuan University, Address 37, Guo Xue Lane, Chengdu, 610041, Sichuan, China.

Introduction: PITX3 has been reported to be associated with congenital cataracts, anterior segment mesenchymal dysgenesis, Peters' anomaly, and microphthalmia. In this case, an infant with unilateral buphthalmos, corneal staphyloma and corneal fistula carrying a variant in PITX3 was reported.

Case Description: We describe a 4-month-old female infant who was referred to our Eye Clinic because of gradual enlargement of the eyeball in the right eye and whitish opacity in both eyes.

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