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spp., and Threats to the Food Industry and Public Health.
Foodborne Pathog Dis
January 2025
Departamento de Alimentos e Nutrição Experimental, Faculdade de Ciências Farmacêuticas, Universidade de São Paulo, São Paulo, Brazil.
Foodborne pathogens have always been of public health concern and represent safety issues for food processors. These pathogens develop new ways to overcome antibiotics, survive in different environmental conditions, and the ability to reproduce in many hostile environments configure them as serious health hazards. Considering the huge number of microorganisms, three bacterial representatives were selected to provide a better knowledge about the question of which one is the worst enemy for humans, from the food industry point of view, taking into consideration their multiplication specificity, virulence, and resistance.
View Article and Find Full Text PDFAdvancing Phage Therapy: A Comprehensive Review of the Safety, Efficacy, and Future Prospects for the Targeted Treatment of Bacterial Infections.
Infect Dis Rep
November 2024
Drug Discovery and Development, Creative Biolabs Inc., Shirley, NY 11967, USA.
Background: Phage therapy, a treatment utilizing bacteriophages to combat bacterial infections, is gaining attention as a promising alternative to antibiotics, particularly for managing antibiotic-resistant bacteria. This study aims to provide a comprehensive review of phage therapy by examining its safety, efficacy, influencing factors, future prospects, and regulatory considerations. The study also seeks to identify strategies for optimizing its application and to propose a systematic framework for its clinical implementation.
View Article and Find Full Text PDFEffectiveness of a bacteriophage YZU_PF006 in controlling dairy spoilage caused by Pseudomonas fluorescens.
J Dairy Sci
December 2024
School of Food Science and Engineering, Yangzhou University, Yangzhou, Jiangsu, 225127 China; Yangzhou Engineering Research Center of Food Intelligent Packaging and Preservation Technology, Yangzhou, Jiangsu, 225127 China. Electronic address:
Pseudomonas fluorescens is a psychrophilic bacterium that can cause dairy spoilage by producing heat-stable enzymes. Bacteriophages are proved as one of the alternatives to control spoilage bacteria in today's dairy industry. This study aimed to investigate how a previously identified phage YZU_PF006 prevents dairy spoilage caused by P.
View Article and Find Full Text PDFThe induction of polyamines metabolism pathway and membrane stability with silicon alleviate the vanadium toxicity in pepper plants.
J Hazard Mater
November 2024
National Key Laboratory for Tropical Crop Breeding, School of Breeding and Multiplication (Sanya Institute of Breeding and Multiplication), Hainan University, Sanya 572025, China; Key Laboratory for Quality Regulation of Tropical Horticultural Crops of Hainan Province, School of Tropical Agriculture and Forestry, Hainan University, Haikou 570228, China. Electronic address:
The vanadium (V) toxicity predominantly is the primary limitation in restraining pepper growth. The silicon (Si) in pepper plants induced the transcript level of the polyamines metabolism pathway genes, including the arginase (CbARG), ornithine decarboxylase (CbODC), arginine decarboxylase (CbADC), N-carbamoylputrescine amidase (CbNCA), Spermidine synthase (CbSPDS), copper binding diamine oxidase (CbCuAO) to overcome the V toxicity. The polyamines, including the Spm, Spd, and Put, induced with Si about 41.
View Article and Find Full Text PDFA privacy-preserving approach for cloud-based protein fold recognition.
Patterns (N Y)
September 2024
Medical Data Privacy and Privacy Preserving Machine Learning (MDPPML), Department of Computer Science, University of Tübingen, 72076 Tübingen, Germany.
The complexity and cost of training machine learning models have made cloud-based machine learning as a service (MLaaS) attractive for businesses and researchers. MLaaS eliminates the need for in-house expertise by providing pre-built models and infrastructure. However, it raises data privacy and model security concerns, especially in medical fields like protein fold recognition.
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