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Tailored large-particle quantum dots with high color purity and excellent electroluminescent efficiency.

Sci Bull (Beijing)

January 2025

Jiangsu Key Laboratory for Carbon-Based Functional Materials & Devices, Institute of Functional Nano & Soft Materials (FUNSOM), Soochow University, Suzhou 215123, China; Macao Institute of Materials Science and Engineering (MIMSE), MUST-SUDA Joint Research Center for Advanced Functional Materials, Zhuhai MUST Science and Technology Research Institute, Macau University of Science and Technology, Macao 999078, China; Institute of Organic Optoelectronics (IOO), Jiangsu Industrial Technology Research Institute (JITRI), Suzhou 215200, China. Electronic address:

High-quality quantum dots (QDs) possess superior electroluminescent efficiencies and ultra-narrow emission linewidths are essential for realizing ultra-high definition QD light-emitting diodes (QLEDs). However, the synthesis of such QDs remains challenging. In this study, we present a facile high-temperature successive ion layer adsorption and reaction (HT-SILAR) strategy for the growth of precisely tailored ZnCdSe/ZnSe shells, and the consequent production of high-quality, large-particle, alloyed red CdZnSe/ZnCdSe/ZnSe/ZnS/CdZnS QDs.

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VG@nAu-based fluorescent biosensor for grading Alzheimer's disease by detecting P-tau181 protein in clinical samples.

Anal Chim Acta

February 2025

Institute for Advanced Study (IAS), College of Life Sciences and Oceanography, Shenzhen University, Shenzhen, Guangdong, 518060, China. Electronic address:

Background: Alzheimer's disease (AD) is a neurodegenerative disorder with a very long duration, posing a serious threat to people's life and health. To date, no medicine that can cure or reverse the disease has been developed or reported, so early diagnosis and timely intervention are essential. The concentration of Phosphorylated tau181 (P-tau181) in blood has been approved by FDA as a standard for assisting clinical diagnosis of AD.

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Background: Evidence from preclinical studies suggests that IL-6 signalling has the potential to modulate immunopathogenic mechanisms upstream of autoantibody effector mechanisms in patients with generalised myasthenia gravis. We aimed to assess the safety and efficacy of satralizumab, a humanised monoclonal antibody targeting the IL-6 receptor, in patients with generalised myasthenia gravis.

Methods: LUMINESCE was a randomised, double-blind, placebo-controlled, multicentre, phase 3 study at 105 sites, including hospitals and clinics, globally.

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Mechanosynthesis of fluorescent magnetic alumina for latent fingerprint detection.

J Colloid Interface Sci

January 2025

iBB-Institute for Bioengineering and Biosciences and i4HB-Institute for Health and Bioeconomy, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal; Bioengineering Department, Instituto Superior Técnico, Universidade de Lisboa, Av. Rovisco Pais, 1049-001 Lisboa, Portugal.

A green approach towards the synthesis of both conventional and magnetic fluorescent powders for revealing latent fingerprints (FPs) is disclosed. The powders formulation is based on a biodegradable matrix and fluorescent dyes extracted from commercial felt-tip markers. Two classes of powders are described: one with a fluorescent component, and other with both fluorescent and magnetic components.

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The estimation of peripheral dose (PD) is vital in cancer patients with long life expectancy. Assessment of PD to radiosensitive organs is important to determine the possible risk of late effects. An attempt has been made to assess the peripheral dose using optically stimulated luminescence dosimeter (OSLD) with megavoltage photon beams as a function of field size, depth, energy, and distance from the field edge.

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