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Article Synopsis
  • Ascorbic acid is essential for the body, promoting collagen health, but its imbalance can lead to diseases like scurvy and cardiovascular issues.
  • A new biosensor using iron-doped hydroxyapatite was developed for cost-effective, real-time colorimetric detection of ascorbic acid, taking advantage of the material's large surface area and catalytic properties.
  • The sensor shows a linear detection range from 0.6 to 56 μM with rapid response time (75 seconds) and can measure ascorbic acid levels in physiological solutions effectively.
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Vitamin C deficiency can lead to pulmonary hypertension: a systematic review of case reports.

BMC Pulm Med

March 2024

Department of Intensive Care Medicine, Amsterdam University Medical Centers, location VUmc, Amsterdam, The Netherlands.

Background: In the early literature, unintentional vitamin C deficiency in humans was associated with heart failure. Experimental vitamin C deficiency in guinea pigs caused enlargement of the heart. The purpose of this study was to collect and analyze case reports on vitamin C and pulmonary hypertension.

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Research Background: The rowan ( L.) is a small tree in the Rosaceae family with characteristic orange-red fruits. The raw fruits can be used for making jams, juices and puree, while the dried fruits are used for teas.

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Ascorbate deficiency increases progression of shigellosis in guinea pigs and mice infection models.

Gut Microbes

December 2023

Institut de Biologie Moléculaire et Cellulaire, Architecture et Réactivité de l'ARN, Université de Strasbourg, Strasbourg, France.

spp. are the causative agents of bacterial dysentery and shigellosis, mainly in children living in developing countries. The study of entire life cycle and the evaluation of vaccine candidates' protective efficacy have been hampered by the lack of a suitable animal model of infection.

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Objective: The macromorphological characteristics and frequency of endocranial abnormal blood vessel impressions (ABVI) and periosteal appositions of dura mater (PADM), and their association with sex, age-at-death and scurvy-like lesions were studied. The possible etiologies of these lesions were discussed.

Materials: A total of 144 adult skulls excavated from an early modern (16th-19th c.

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