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Prevalence and genomic insights of carbapenem resistant and ESBL producing Multidrug resistant Escherichia coli in urinary tract infections.
Sci Rep
January 2025
Department of Biotechnology, Faculty of Biomedical Sciences and Technology, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Porur, Chennai, India.
Urinary tract infections are a common condition affecting people globally, with multidrug-resistant (MDR) Escherichia coli (E. coli) being a major causative agent. Antimicrobial susceptibility profiling was performed using the VITEK 2 automated system for 1254 E.
View Article and Find Full Text PDFThe fluoroquinolone compounds potentiate the antifungal activity of the echinocandins against Aspergillus fumigatus.
Biosci Rep
January 2025
Korea University, Seoul, Korea (South), Republic of.
The antifungal drugs of the echinocandin family show high efficacy against Aspergillus fumigatus. However, their paradoxical effect, which restores fungal growth at high drug concentrations, and the emergence of resistant strains necessitate improvements. We identified 13 fluoroquinolone compounds from a chemical library containing 10,000 compounds that potentiate the antifungal activity of caspofungin.
View Article and Find Full Text PDFHouseflies (Musca domestica) as vectors of multidrug-resistant, ESBL-producing Escherichia coli in broiler poultry farms of North India: implications for antibiotic resistance transmission.
Environ Sci Pollut Res Int
January 2025
Gut Biology Laboratory, Room No. 117, Department of Zoology, University of Delhi, New Delhi, 110007, India.
The transmission of antibiotic resistance (AR) from farm animals to healthy human communities, beyond the food chain, is often facilitated by biological vectors, notably houseflies (Musca domestica). This study aimed to evaluate the role of M. domestica collected from commercial broiler chicken farms as a carrier of multidrug-resistant (MDR), extended-spectrum β-lactamase (ESBL)-producing Escherichia coli.
View Article and Find Full Text PDFAntimicrobial Usage and Antimicrobial Resistance in Commensal from Broiler Farms: A Farm-Level Analysis in West Java, Indonesia.
Antibiotics (Basel)
December 2024
Division of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, 3584 CL Utrecht, The Netherlands.
Antimicrobial resistance (AMR) is a global public health threat, with antimicrobial use (AMU) in livestock recognized as a significant driver. This study examines farm-level AMU and AMR as well as the relationship between AMU and AMR on broiler farms in Indonesia. Data were collected from 19 farms in West Java between 2019 and 2021 to examine AMU in depth across four to five successive production cycles.
View Article and Find Full Text PDFAntimicrobial resistance pattern of isolated from imported frozen shrimp in Saudi Arabia.
PeerJ
December 2024
Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Imam Abdulrahman Bin Faisal University, Dammam, Eastern Region, Saudi Arabia.
Contamination of seafood products with multi-drug-resistant (MDR) bacteria is considered to be a potential source for the spread of MDR bacteria in communities. However, little is known about the extent of the contamination of seafood, in particular shrimp, with MDR bacteria in Saudi Arabia. In this study, imported frozen shrimp in retail markets were examined for the antimicrobial susceptibility patterns of .
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