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Serology and histology in Sjögren's syndrome diagnosis: a retrospective accuracy study.
Clin Rheumatol
January 2025
Department of Dentistry-Division of Oral Medicine, Oral Pathology and Radiology, and Division of Dental Hygiene, Faculty of Medicine and Dentistry, University of Alberta, Room 5-357 Edmonton Clinic Health Academy, 11405 87 Avenue NW, Edmonton, AB, Canada.
Introduction: Sjögren's syndrome (SS) presents complex diagnostic challenges due to its multi-organ involvement, often leading to misdiagnosis, which can result in unnecessary treatments, elevated healthcare costs, and significant impacts on patient quality of life. Accurate diagnosis is therefore critical, utilising ACR/EULAR criteria that include both labial minor salivary gland (LMSG) biopsy and anti-SSA antibodies.
Methods: This retrospective study analysed medical records of 87 adults suspected of primary SS, who underwent both anti-SSA serology and LMSG biopsy.
Dogs are a susceptible species to human adenovirus 36 infection: New insights into the host range of the virus causing infectious obesity.
Vet Microbiol
January 2025
Division of Microbiology, Department of Pathology, Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, C.K. Norwida 31 Street, Wrocław 50-375, Poland. Electronic address:
The prevalence of obesity within the human population is escalating globally yearly. Obesity constitutes a complex ailment with diverse etiological factors. Recently, the infectious side of obesity aetiology, implicating pathogens such as human adenovirus 36 (HAdV-D36), has gained attention.
View Article and Find Full Text PDFPrevalence of "weak B" phenotypes and their evaluation and differentiation in healthy blood donor population in Eastern India.
Asian J Transfus Sci
November 2023
Department of Transfusion Medicine, Apollo Multispeciality Hospitals, Kolkata, West Bengal, India.
Background: Examples of group B red cells that react weakly or not at all with anti-B have been described. Subgroups of B such as B, B, B, and B are rare and are less frequently reported. We studied the frequency of subgroups of B in our healthy blood donor population and serologically characterized and differentiated these subgroups.
View Article and Find Full Text PDFSerological comparison of weak D versus weakly reacting D by four different methods.
Asian J Transfus Sci
September 2022
Department of Transfusion Medicine, Institute of Medical Sciences and SUM Hospital, Bhubaneswar, Odisha, India.
Introduction: Weak D red cells were defined as having a reduced amount of D antigen (formerly called "Du") that required an indirect antiglobulin test (IAT) for detection. Weakly reacting D is those which give <2+ reactions on routine methods. The present study is sharing our experience on weak D and weakly positive anti-D in various methods.
View Article and Find Full Text PDFEvaluating the economic viability of hepatitis E virus serological screening among blood donors: A prospective study from India for advancing blood safety.
Asian J Transfus Sci
December 2024
Department of Microbiology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India.
Background: Hepatitis E virus (HEV) stands out as a significant transfusion-transmissible infection, yet it is not included in the screening protocols of many countries. The present study was conducted to assess the cost-benefit implications of incorporating HEV screening among blood donors which is one of the preventive strategies in reducing transfusion transmissible HEV.
Methodology: A decision tree model was prepared to assist the cost-benefit analysis.
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