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Eumycetoma Caused by Aspergillus terreus: A Case Report and Literature Review.
Am J Trop Med Hyg
December 2024
Department of Dermatology, The Second Hospital of Jilin University, Changchun, People's Republic of China.
Mycetoma is a granulomatous disease of subcutaneous tissue that is caused by different species of aerobic filamentous bacteria (actinomycetoma) or fungi (eumycetoma). Mycetoma treatment depends on the causative pathogen, and it mainly consists of antimicrobial interventions or surgery. Aspergillus terreus is an etiologic agent of invasive aspergillosis and a rare cause of eumycetoma that is common in central and southern China.
View Article and Find Full Text PDFRandomized controlled trial parallel-group on optimizing community pharmacist's care for the elderly: The influence of WhatsApp-Email delivered clinical case scenarios.
PLoS One
October 2024
Department of Basic Medical Sciences, College of Medicine, Dar Al Uloom University, Riyadh, KSA.
Background: Drug-related problems (DRPs) significantly threaten the safety of the elderly. In order to improve pharmacists' ability to minimize these events, novel educational interventions that consider the current challenges in clinical practice are crucial.
Objectives: The primary objective is to assess the impact of two unique educational interventions on pharmacists' ability to identify DRPs.
Impact of COVID-19 on the neglected tropical diseases: a scoping review.
Infect Dis Poverty
July 2024
Infection Medicine, Edinburgh Medical School: Biomedical Sciences, College of Medicine and Veterinary Medicine, The University of Edinburgh, 1 George Square, Edinburgh, EH8 9TB, Scotland, UK.
Article Synopsis
- This study examines how the COVID-19 pandemic has impacted neglected tropical diseases (NTDs), focusing on funding and program management, and evaluates potential delays to the Sustainable Development goals for elimination of these diseases.
- Researchers used data from various official sources like the World Health Organization and government aid documents to analyze the pandemic's effects on NTD management, funding, and barriers faced by low and middle-income countries.
- Results show that the pandemic caused significant disruptions in NTD programs, leading to a decline in research and development funding, and negatively affecting the progress towards eliminating these diseases, especially in poorer populations.
Naphthylisoquinoline alkaloids: novel agents against the causative pathogens of eumycetoma and actinomycetoma- to broad-spectrum antimycetomal drugs.
Antimicrob Agents Chemother
May 2024
Institute of Organic Chemistry, University of Würzburg, Würzburg, Germany.
Mycetoma is a devastating neglected tropical infection of the subcutaneous tissues. It is caused by fungal and bacterial pathogens recognized as eumycetoma and actinomycetoma, respectively. Mycetoma treatment involves diagnosing the causative microorganism as a prerequisite to prescribing a proper medication.
View Article and Find Full Text PDFThe flavonoid luteolin reduces mutant huntingtin aggregation and cytotoxicity in huntingtin-mutated neuroblastoma cells.
Saudi Pharm J
December 2023
Department of Pharmacy Practice, Unaizah College of Pharmacy, Qassim University, Buraydah 52571, Saudi Arabia.
Background: Huntington's disease is an inherited progressive neurodegenerative disorder caused by an expansion of the polyglutamine tract leading to malformation and aggregation of the mutant huntingtin protein in the cell cytoplasm and nucleus of affected brain regions. The development of neuroprotective agents from plants has received considerable research attention.
Objective: Our study aims to investigate the neuroprotective effects of luteolin and the mechanisms that underline its potential mediated protection in the mutant htt neuroblastoma cells.
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