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A resource of longitudinal RNA-seq data of Holstein cow rumen, duodenum, and colon epithelial cells during the lactation cycle.

BMC Genom Data

January 2025

Animal Genomics and Improvement Laboratory, BARC, Agricultural Research Service, USDA, Beltsville, MD, 20705, USA.

As one of the most important ruminant breeds, Holstein cattle supply a significant portion of milk and dairy for human consumption, playing a crucial role in agribusiness. The goal of our study was to examine the molecular adaptation of gastrointestinal tissues that facilitate milk synthesis in dairy cattle. DATA DESCRIPTION: We performed RNA-seq analysis on epithelial cells from the rumen, duodenum, and colon at eight different time points: Days 3, 14, 28, 45, 120, 220, and 305 in milk, as well as the dry period.

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Hidden hunger: from a plant biologist's perspective.

J Sci Food Agric

January 2025

School of Biosciences, Faculty of Science and Engineering, University of Nottingham Malaysia, Semenyih, Malaysia.

In recent years, changes in dietary patterns from an omnivore diet to a moderate-to-restrictive diet that includes more plant food are becoming popular for various reasons and the associated health benefits. Despite the increased consumption of plant food as recommended by these seemingly healthy diets, micronutrient deficiency is still prevalent particularly among the health-conscious populations. The aim of this review is to help guide interventions by understanding micronutrient deficiency trends from a dietary habit and plant physiology context.

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Background: Childhood obesity and the rate of its spread is a serious threat to the reproductive health of the nation, especially among boys, being a background for delaying sexual development and further disrupting fertility.

Aim: To study the peculiarities of the ratio of the level of leptin and a number of toxic and essential chemical trace elements in biological environments in adolescent boys aged 13-14 years with obesity and delayed sexual development.

Materials And Methods: Three groups of adolescents aged 13-14 years were studied and formed: the main ones - with constitutional exogenous obesity of 1-2 degrees (1-20 boys without secondary signs of puberty; 2 - 24 boys with 2-4 stages of puberty according to Tanner) and comparisons (3 - 15 boys with normal body weight and without deviations in puberty).

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Pharmaceutical supplementation and dietary fortification are the most common approaches to reducing vitamin deficits. To improve the health and nutritional value of crops, agronomic biofortification necessitates the direct application of nutrients. Producers using micronutrient fertilizers to increase the fortification of crops are essential to the success of biofortification.

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Through biochemical transformation of host-derived bile acids (BAs), gut bacteria mediate host-microbe crosstalk and sit at the interface of nutrition, the microbiome, and disease. BAs play a crucial role in human health by facilitating the absorption of dietary lipophilic nutrients, interacting with hormone receptors to regulate host physiology, and shaping gut microbiota composition through antimicrobial activity. Bile acid deconjugation by bacterial bile salt hydrolase (BSH) has long been recognized as the first necessary BA modification required before further transformations can occur.

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