This is apparently the second report of a case of human meningoencephalitis caused by the nematode Micronema deletrix. The patient had severe granulomatous meningoencephalitis with numerous foci of hemorrhage and encephalomalacia. Numerous adult female and larval M. deletrix were in the brain. The organisms probably inhabit decaying organic material, but occasionally parasitize the kidney, nose, or central nervous system of the horse. In its parasitic form the nematode replicates parthenogenetically.
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http://dx.doi.org/10.1093/ajcp/72.4.640 | DOI Listing |
J Clin Microbiol
May 2015
Department of Microbiology, SA Pathology, Adelaide, South Australia, Australia.
Halicephalobus gingivalis (previously Micronema deletrix) is a free-living nematode known to cause opportunistic infections, mainly in horses. Human infections are very rare, but all cases described to date involved fatal meningoencephalitis. Here we report the first case of H.
View Article and Find Full Text PDFEquine Vet J
November 2011
Department of Pathology and Infectious Diseases, Royal Veterinary College, Hatfield, Hertfordshire, UK.
A fatal case of eosinophilic and granulomatous meningoencephalitis caused by the free-living panagrolaimid nematode Halicephalobus gingivalis is reported in a 10-year-old Welsh gelding in the United Kingdom. Clinical examination first revealed behavioural abnormalities which rapidly progressed to severe ataxia, reduced mentation status and cranial nerve signs. Despite symptomatic treatment no amelioration of neurological signs was achieved and the horse was subjected to euthanasia.
View Article and Find Full Text PDFParasite
September 1998
Department of Zoology, University of Guelph, Ontario, Canada.
Although the original description given by Stefanski (1954) was satisfactory, Anderson & Bemrick (1965), in describing H. deletrix (= Micronema deletrix), claimed Stefanski's description was "inadequate" and the species a "species inquirenda". Thus, infections in horses and humans have been assigned to H.
View Article and Find Full Text PDFTierarztl Prax Ausg G Grosstiere Nutztiere
May 1998
Institut für Veterinär-Pathologie, Justus-Liebig-Universität Giessen sowie.
Therapy resistant swellings of the maxillary region and unilateral nasal discharge in older horses are mainly thought to be consequences of neoplasias of the oral cavity, especially of the gingiva and the teeth, or to develop from tumours of the nasal cavity. We report an unilateral swelling of the left nasal and buccal region in a 13-year-old gelding, which was accompanied by an aggressive destruction of involved osseous tissue due to a severe proliferative granulomatous inflammation. The granuloma was caused by the nematode Halicephalobus (syn.
View Article and Find Full Text PDFJ Am Vet Med Assoc
September 1996
Department of Large Animal Surgery, Tufts University School of Veterinary Medicine, North Grafton, MA 01536, USA.
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