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We studied the evolution of chronic Chagas' disease in 107 patients with a positive Guerreiro-Machado reaction and 22 non-chagasic, non-heart disease control subjects for a follow-up period of 3 to 10 years (mean follow-up of 4.9 years). After completion of invasive and non-invasive studies, chagasic patients were classified into four groups: IA (normal ECG, without heart disease; 18 patients); IB (normal ECG, early left ventricular segmental abnormalities; 13 patients); II (abnormal ECG, advanced myocardial damage, no signs of heart failure; 42 patients); and III (abnormal ECG, end-stage, congestive heart failure; 34 patients).
View Article and Find Full Text PDF[Guerreiro Machado reaction. Chromatographic analysis of Trypanosoma cruzi antigens].
Mem Inst Oswaldo Cruz
August 1985
The aqueous extract of Trypanosoma cruzi, previously treated by benzene, was filtered through a column of Sephadex G-200. The eluted fractions were tested by complement-fixation with the chagasic reference serum. It was found that the CF antigens were eluted in the first fractions and the contaminants in the last ones.
View Article and Find Full Text PDF[Association between the positivity of the Guerreiro Machado reaction and the abreuographic result of cardiomegaly].
Rev Bras Malariol Doencas Trop
January 1985
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