Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Essential tremor - drug treatments present and future.
Expert Rev Neurother
December 2024
Section of Neurology, Hospital Universitario del Sureste, Arganda del Rey, Madrid, Spain.
Introduction: The main treatment options for essential tremor (ET), which is probably one of the most common movement disorders, have been propranolol and primidone, for many years. This review aims to synthesize therapeutic attempts with other drugs.
Areas Covered: We have reviewed the current state of the pharmacological treatment of ET, both in patients and in experimental models of this disease, with special emphasis on the data published in the last 5 years.
Ten years of monitoring pharmaceuticals and pesticides in the aquatic environment nearby a solid-waste treatment plant: Historical data, trends and risk assessment.
Environ Pollut
December 2024
Environmental and Public Health Analytical Chemistry, Research Institute for Pesticides and Water, University Jaume I, Castelló, Spain. Electronic address:
The emission of contaminants of emerging concern (CECs) from wastewater treatment plants has been extensively studied; however, less attention has been paid to municipal solid waste treatment plants (MSWTPs), which can also be a potential source for CECs into surface water (SW) and groundwater (GW) ecosystems. In this work, the environmental impact of a MSWTP located in the province of Castelló, Spain, was studied along a period of ten years (from 2012 to 2022). A total of 173 water samples (including SW and GW) collected from the surrounding of this plant were monitored for 93 compounds (pharmaceuticals and pesticides) by using liquid chromatography coupled to tandem mass spectrometry with triple quadrupole.
View Article and Find Full Text PDFDrug-associated congenital anomalies of the external ear identified in the United States food and drug administration adverse event reporting system database.
Sci Rep
October 2024
Department of Plastic and Reconstructive Surgery, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Article Synopsis
- * The study utilized data from the FAERS database, analyzing over 20 million adverse event reports from 2004 to 2024, focusing on cases related to ear anomalies.
- * Drugs such as primidone and valproic acid were found to have significant associations with these anomalies, indicating potential risks linked to certain medications during pregnancy.
Mechanisms of tremor-modulating effects of primidone and propranolol in essential tremor.
Parkinsonism Relat Disord
November 2024
Department of Neurology, University Medical Centre Ljubljana, Ljubljana, Slovenia; Medical Faculty, University of Ljubljana, Ljubljana, Slovenia. Electronic address:
Introduction: Primidone and propranolol are primary treatments for essential tremor, however the exact mechanisms underlying their efficacy are not fully elucidated. Understanding how these medications alleviate tremor may guide the development of additional pharmacologic treatments. Our prospective observational study employed transcranial magnetic stimulation (TMS) to explore mechanisms of primidone and propranolol effects in essential tremor.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!