Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/978-1-4757-0926-1_23 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Promotes Follicle Growth Through the PI3K/AKT Signaling Pathway In Vivo and In Vitro in Rat.
Food Sci Nutr
December 2024
Key Laboratory of TCM Pharmacology Jilin Academy of Chinese Medicine Sciences Changchun Jilin P.R. China.
The development status of follicles determines the menstrual cycle and estrogen levels, which is crucial to women's health. is a natural product for both medicine and food, which has "estrogenic effect". However, few studies have systematically elaborated its mechanism of action.
View Article and Find Full Text PDF[Mechanism of Yuzhi Zhixue Granules in treating polycystic ovary syndrome in rats].
Zhongguo Zhong Yao Za Zhi
October 2024
School of Pharmacy, Shandong University of Traditional Chinese Medicine Ji'nan 250355, China State Key Laboratory of Integration and Innovation of Classic Formula and Modern Chinese Medicine, Lunan Pharmaceutical Group Co., Ltd. Linyi 273400, China.
This study aims to explore the therapeutic effect of Yuzhi Zhixue Granules on polycystic ovary syndrome(PCOS) in rats and explain the underlying mechanism by metabolomics. Rats were randomized into normal, model, low-, medium-, and high-dose(0.5, 1.
View Article and Find Full Text PDFThe sustained consumption of sucrose-rich diet has deleterious effects on the adrenal cortex, impairing its steroidogenic capacity. As hemin treatment has been shown to exert cytoprotective effects (e.g.
View Article and Find Full Text PDFMolecular Imaging of Renin Activity using Fluorogenic Nanoprobes for Precision Antihypertensive Therapy.
Angew Chem Int Ed Engl
September 2024
State Key Laboratory of Anti-Infective Drug Discovery and Development, School of Pharmaceutical Sciences, Sun Yat-sen University, 510006, Guangzhou, China.
Life-threatening hypertension remains inadequately controlled in clinics due to its heterogeneous renin levels. Rapid stratification of hypertension through renin analysis is crucial for effective personalized treatment, yet an ultrasensitive detection approach is currently lacking. Here, we report activatable renin nanoprobes (ARNs) for non-invasive and ultrasensitive profiling of renin activity and guiding antihypertensive treatment decision through near-infrared fluorescence (NIRF) in vivo imaging and in vitro urinalysis.
View Article and Find Full Text PDFQingda Granule Attenuates Hypertension-Induced Cardiac Damage via Regulating Renin-Angiotensin System Pathway.
Chin J Integr Med
September 2024
Xiyuan Hospital, National Cardiovascular Clinical Medical Research Center of Traditional Medicine, Beijing, 100091, China.
Objective: To assess the efficacy of Qingda Granule (QDG) in ameliorating hypertension-induced cardiac damage and investigate the underlying mechanisms involved.
Methods: Twenty spontaneously hypertensive rats (SHRs) were used to develope a hypertension-induced cardiac damage model. Another 10 Wistar Kyoto (WKY) rats were used as normotension group.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!