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Background: Hypothyroidism is a common sequela after radiotherapy for nasopharyngeal carcinoma (NPC). Magnetic resonance imaging (MRI) has gained prominence in thyroid imaging, leveraging its non-ionizing radiation, high spatial resolution, multiparameter and multidirectional imaging. Few previous studies have investigated the evaluation of radiation-induced thyroid injury by MRI.
View Article and Find Full Text PDFBalancing act: optimizing blue light for melanogenesis while minimizing cellular damage in primary human skin cells.
Front Physiol
January 2025
Regenerative Medicine Division, CHU de Quebec - Université Laval Research Centre, Quebec City, QC, Canada.
Introduction: Recent findings show that visible light, particularly blue light, stimulates melanogenesis in human skin, though the underlying mechanisms remain debated. This study aimed to determine the cell damage threshold of non-ionizing blue light on keratinocytes while preserving their ability to stimulate melanogenesis.
Methods: Human keratinocytes (N = 3) and melanocytes (N = 3) were isolated from skin samples of varying Fitzpatrick skin phototypes and irradiated with blue light (λpeak = 457 nm) and UVA light (λpeak = 385 nm).
Graphene-Integrated Microbolometer Array Imaging System: A Novel Approach for Fast and Sensitive Terahertz Detection in Biomedical Applications.
ACS Appl Mater Interfaces
January 2025
Advanced Micro-/Nano- Devices Lab, Department of Systems Design Engineering, University of Waterloo, 200 University Ave West, Waterloo, Ontario N2L 3G1, Canada.
Existing biomedical imaging modalities are often restricted by their substantial size, high costs, and potential risks associated with ionizing radiation exposure. Given these challenges, there is an urgent need for innovative imaging systems that not only excel in detection performance but are also compact, cost-effective, and ensure safety for biomedical applications. In response to these requirements, our research introduces an advanced terahertz (THz) microbolometer array imaging system (MAIS), specifically engineered for biomedical detection.
View Article and Find Full Text PDFComparison of Acute and Protracted Gamma Irradiation Effects During Perinatal Development in Beagle Dogs.
Radiat Res
January 2025
Medical Sciences Division, Northern Ontario School of Medicine, Sudbury, ON P3E 2C6 Canada.
Ionizing radiation exposure during perinatal development can produce various biological effects on the developing offspring. These effects are dependent on a number of factors, including total dose, dose rate and the developmental processes occurring at the time of irradiation. The present study conducted an analysis of historical radiobiological archived data involving 60Co-gamma irradiation of beagle dogs at specific periods of prenatal or postnatal development.
View Article and Find Full Text PDFAssessment of the effectiveness of Monte Carlo Simulation for dose control at the Moroccan Boukhalef ionization facility.
Appl Radiat Isot
January 2025
Department of Physics, Nuclear Physics and Techniques Team, Faculty of Science, Ibn Tofail University, Kenitra, Morocco.
Controlling the absorbed dose received by a target is a major challenge encountered during ionizing radiation applications. For experimentally measuring absorbed dose, dosimetric systems are used. On the other hand, in addition to experimental methods of dose measurement, there are other alternatives for calculating absorbed doses, these are numerical methods based on the Monte Carlo method which are very sophisticated and widely used throughout the world.
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