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Insider apology for microeconomic theorising?

J Econ Methodol

March 2024

Department of Economic History, London School of Economics, London, England.

This comment on 'Economic theories and their Dueling interpretations' questions the descriptive adequacy of the 'sociology of economics' proposed by Gilboa, Postlewaite, Samuelson, and Schmeidler (GPSS) (2022). We ask whether economists still perceive the role of microeconomic theory as central as do GPSS. In particular, is present-day economics unified by the principles of maximising, subject to constraints and equilibrium analysis? We argue that this is not the case.

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Protein binding and folding through an evolutionary lens.

Curr Opin Struct Biol

January 2025

Department of Medical Biochemistry and Microbiology, Uppsala University, BMC, Box 582, SE-75123 Uppsala, Sweden. Electronic address:

Protein-protein associations are often mediated by an intrinsically disordered protein region interacting with a folded domain in a coupled binding and folding reaction. Classic physical organic chemistry approaches together with structural biology have shed light on mechanistic aspects of such reactions. Further insight into general principles may be obtained by interpreting the results through an evolutionary lens.

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In many scientific fields, sparseness and indirectness of empirical evidence pose fundamental challenges to theory development. Theories of the evolution of human cognition provide a guiding example, where the targets of study are evolutionary processes that occurred in the ancestors of present-day humans. In many cases, the evidence is both very sparse and very indirect (e.

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Article Synopsis
  • Respecting patient autonomy is essential in medicine, but can clash with the principles of beneficence (doing good) and nonmaleficence (doing no harm), especially in complex cases like oral health care.
  • The study analyzed scholarly articles to understand how this ethical conflict arises and how it has been addressed in clinical scenarios, particularly in maxillofacial treatments.
  • The results showed that while most recommendations leaned towards prioritizing medical benefits for the patient, there were also instances where patient autonomy was upheld, particularly for preventive care or low-impact interventions.
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Marcus Tullius Cicero's concept of "ius gentium," or universal law, provides a timeless framework for understanding and defending fundamental human rights, particularly in the context of reproductive freedom. Cicero distinguished between "ius gentium" and "ius civile," emphasizing that while civil law governs specific communities, universal law, rooted in natural reason, applies to all humanity. This philosophical foundation resonates with modern discussions on reproductive rights, where universal principles of justice and bodily autonomy are at stake.

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