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Are Collagen Protons Visible with the Zero Echo Time (ZTE) Magnetic Resonance Imaging Sequence: A DO Exchange and Freeze-Drying Study.
Bioengineering (Basel)
December 2024
Department of Radiology, University of California San Diego, San Diego, CA 92037, USA.
It is known that ultrashort echo time (UTE) magnetic resonance imaging (MRI) sequences can detect signals from water protons but not collagen protons in short T2 species such as cortical bone and tendons. However, whether collagen protons are visible with the zero echo time (ZTE) MRI sequence is still unclear. In this study, we investigated the potential of the ZTE MRI sequence on a clinical 3T scanner to directly image collagen protons via DO exchange and freeze-drying experiments.
View Article and Find Full Text PDFA hemoadhican-based sponge with anti-heparin interference for treating uncontrollable massive hemorrhage.
Int J Biol Macromol
November 2024
Center for Molecular Metabolism, Nanjing University of Science & Technology, Nanjing, 210094, China; Key laboratory of Metabolic Engineering and Biosynthesis Technology, Ministry of Industry and Information Technology, 210094, China. Electronic address:
Hemoadhican (HD) is an exopolysaccharide with a branched structure that has been reported for its high hemostatic ability. In this study, a HD-based hemostatic sponge was prepared through ultrasonic dissolution and freeze-drying without using any cross-linking agent. The sponge could spontaneously cross-link using hydrogen bonds to form adhesive mud within 3 s upon contact with blood.
View Article and Find Full Text PDFEvaluation and comparison of autologous particulate dentin with demineralized freeze dried bone allograft in ridge preservation procedures - a prospective clinical study.
Clin Oral Investig
August 2024
Department of Periodontics and Implantology, Vishnu dental college, Vishnupur, Bhimavaram, West Godavari, West Godavari, Andhra Pradesh, 534202, India.
Article Synopsis
- The study aimed to compare the effectiveness of Autologous Particulate Dentin (APD) and Demineralized Freeze-Dried Bone Allograft (DFDBA) in preserving jawbone ridges after tooth extraction, analyzing both clinical and radiographic outcomes.
- Thirty participants had their mandibular posterior teeth extracted and were divided into two groups to receive either APD or DFDBA mixed with i-PRF, with assessments conducted before and six months after the procedure.
- Results showed that while both groups experienced a decrease in ridge dimensions, the APD group had less reduction in horizontal ridge width compared to the DFDBA group, indicating APD may be a more effective option for ridge preservation.
Preparation of sp carbon-bonded π-conjugated COF aerogels by ultrasound-assisted mild solvothermal reaction for multi-functional applications.
Nanoscale
August 2024
MOE Key Laboratory of High Performance Polymer Materials & Technology, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Molding COFs into aerogels from monomers can establish interpenetrating spatial network structures on the centimeter scale that increase the accessibility of dominant pore channels and the convenience of real application, which radically gets rid of the difficult reprocessing problems of insoluble and non-fusible powder COFs. However, the construction of bulk COF structures and achieving crystallinity are often incompatible, especially with sp carbon-based COFs, whose powder synthesis has been quite demanding. Herein, for the first time, we report an efficient method to prepare sp carbon-linked π-conjugated DFB-TMTA-COF (DT-COF) aerogels by an ultrasound-assisted mild solvothermal technique and freeze-drying.
View Article and Find Full Text PDFAdditive-free Absorbable Keratin Sponge With Procoagulant Activity for Noncompressible Hemostasis.
Biomacromolecules
July 2024
School of Ophthalmology and Optometry, School of Biomedical Engineering, Wenzhou Medical University, 270 Xueyuan West Road, Wenzhou, Zhejiang 325027, China.
The development of a natural, additive-free, absorbable sponge with procoagulant activity for noncompressible hemostasis remains a challenging task. In this study, we extracted high molecular weight keratin (HK) from human hair and transformed it into a hemostatic sponge with a well-interconnected pore structure using a foaming technique, freeze-drying, and oxidation cross-linking. By controlling the cross-linking degree, the resulting sponge demonstrated excellent liquid absorption ability, shape recovery characteristics, and robust mechanical properties.
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