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"Penosissima, y rigorosa enfermedad" (Most Troublesome and rigorous disease): An analysis of the first medical-moral treatise on epilepsy in Latin America.

Epilepsy Behav

December 2024

Child and Adolescent Neurology Service, Department of Pediatrics, Faculty of Medicine, University of Antioquia, Pediaciencias Research Group, Medellín, Colombia. Electronic address:

Introduction: The influence of the Enlightenment is evident with the mention of Herman Boerhave. The strong European influence draws attention with minimal expression of the social and medical concepts of pre-Colombian cultures such as the Aztec and Mayan.

Methods: A medical and cultural conceptual analysis of the text "Medical-moral report of the very painful, and rigorous disease of epilepsy" is carried out.

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Tagetes erecta L.: A traditional medicine effective in inflammatory process treatment.

J Ethnopharmacol

November 2024

Postgraduate Program in Pharmaceutical Science, Universidade do Vale do Itajaí, Itajaí, Santa Catarina, Brazil. Electronic address:

Ethnopharmacological Relevance: Tagetes erecta L. (Asteraceae), popularly known as Aztec Marigold, is used in folk medicine to treat several ailments including inflammatory processes. Despite its historical use, the specific mechanisms through which it may modulate inflammation, particularly its effects on neutrophils and macrophages activation, have not yet been completely investigated.

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Article Synopsis
  • A study was conducted to determine if the macrolide antibiotic azithromycin can improve survival rates without chronic lung disease in preterm infants born before 30 weeks of gestation.
  • The AZTEC trial involved 799 preterm infants across 28 UK neonatal units and randomly assigned them to receive either azithromycin or a placebo.
  • The primary outcome measured was the survival of infants without developing significant lung disease by 36 weeks postmenstrual age.
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For millennia, healing and psychoactive plants have been part of the medicinal and ceremonial fabric of elaborate rituals and everyday religious practices throughout Mesoamerica. Despite the essential nature of these ritual practices to the societal framework of past cultures, a clear understanding of the ceremonial life of the ancient Maya remains stubbornly elusive. Here we record the discovery of a special ritual deposit, likely wrapped in a bundle, located beneath the end field of a Late Preclassic ballcourt in the Helena complex of the Maya city of Yaxnohcah.

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Ethnopharmacology, Nutritional Value, Therapeutic Effects, Phytochemistry, and Toxicology of L.: A Review.

Curr Top Med Chem

December 2023

Team of Ethnopharmacology and Pharmacognosy, Faculty of Sciences and Techniques Errachidia, Moulay Ismail University of Meknes, BP 509, Boutalamine, Errachidia, 52000, Morocco.

Aims: The purpose of this review was to emphasize the nutritional value, and pharmacological and phytochemical properties of , as well as its toxicological evaluation.

Background: Salvia hispanica L. (), also called chia seeds, is an annual herbaceous plant belonging to the family Lamiaceae.

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