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A 56-year-old male presented to the clinic with complaints of multiple skin lesions. A complete blood count (CBC) was not available. No constitutional symptoms were present, and physical examination revealed tender skin lesions of the back, arms, legs, and scalp.

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The macrocyclic biquinazoline ligand, H-Mabiq, presents a central and a peripheral site for the coordination of metal ions, making the adsorption on solid surfaces promising for the creation of self-assembled bimetallic two-dimensional platforms. Here, we apply an on-surface metalation strategy under ultra-high vacuum conditions to guide the synthesis of metalated species and study sequential metalation patterns. We find that cobalt (as well as iron) metalation on the Ag(111) surface preferentially occurs at the macrocyclic centre without further metal coordination to the peripheral site.

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Syringocystadenoma papilliferum (SCAP) is an uncommon but benign glandular neoplasm, known to arise in association with nevus sebaceus, that can present with variance in morphology. The diverse presentation of SCAP creates a diagnostic challenge that often lends reliance on biopsy for confirmation. In children, this can be an invasive, painful, and undesired procedure.

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Background: Surgical management for bronchiectasis is uncommon. This study reviewed the experience of bronchiectasis surgery and subsequent outcomes at a tertiary paediatric centre over a 20 year period.

Methods: Retrospective audit of children aged < 18 years who underwent bronchiectasis surgery at Starship Children's Hospital between 2001 and 2021.

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Ecotoxicology dilemmas: issues with dose, causality, response, mixtures, and modifying factors.

Environ Toxicol Chem

January 2025

L.S. McCarty Scientific Research & Consulting, Newmarket, Canada.

Ecotoxicology has model assumptions that are the basis of the discipline's scientific validity and regulatory utility. Using testing data to advance knowledge and practical applications is contingent on assumption validation of underlying models, an uncommon practice. Fundamental components-dose, causality, response-are confounded, as test metrics are each accumulations of a multiplicity of factors.

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