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AAPS J
January 2025
Institute of Drug Metabolism and Pharmaceutical Analysis, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, 310058, China.
Freeze drying is one of the common methods to extend the long-term stability of biologicals. Biological products in solid form have the advantages of convenient transportation and stable long-term storage. However, long reconstitution time and extensive visible bubbles are frequently generated during the reconstitution process for many freeze-dried protein formulations, which can potentially affect the management efficiency of staff, patient compliance, and product quality.
View Article and Find Full Text PDFLiver Int
February 2025
Department of Pharmaceutics, School of Pharmacy, Fourth Military Medical University, Xi'an, China.
Open Med (Wars)
January 2025
Department of Toxicological Chemistry, National Poison Control Center, Military Medical Academy, Belgrade, 11000, Serbia.
Introduction: Qualitative and quantitative testing of ethanol in samples is an important analytical procedure that provides accurate, precise, and reliable results. Given the complexity of the issue, obtaining a realistic picture of lifelong alcoholemia requires supporting blood ethanol findings with analyses of alternative samples, primarily vitreous humor (VH).
Objective: The objective of this study was to develop and validate a headspace gas chromatography with flame ionization detection (HS/GC-FID) method for determining ethanol concentration in VH.
Metab Brain Dis
January 2025
Department of Pharmacy, Jiangbei Campus of The First Affiliated Hospital of Army Medical University (No. 958 Hospital of PLA Army), Chongqing, 400020, China.
To explore the pharmacological mechanism of Changpu-Yizhi-Wan (CYW) in the treatment of Alzheimer's disease (AD) from the perspective of ferroptosis based on network pharmacology and experimental verification. The Encyclopedia of Traditional Chinese Medicine 2.0 (ETCM2.
View Article and Find Full Text PDFBMC Sports Sci Med Rehabil
January 2025
Department of Pharmacy, The 969 th Hospital of P.L.A, Hohhot, 010051, China.
Background: Heat stroke, a severe heat illness with organ damage, is a major cause of cause irreparable organ damage and higher death rates among military persons and athletes.
Objectives: To study the changes in blood lactate (Lac) levels and lactate clearance rate (LCR) in athletes with heat illness of varying degrees after high-intensity exercise and to evaluate their prognostic value.
Material And Methods: In present study, acute care unit admitted 36 heat sickness patients following high-intensity exercise from December 2019 to July 2024, with comprehensive medical records, for retrospective study.
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