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Early Prognostic Markers for Idiopathic Facial Palsy.
Laryngoscope
January 2025
Otolaryngology Department, Hospital Universitario Ramón y Cajal, Madrid, Spain.
Objectives: To analyze the prognostic value of markers available at the onset of idiopathic facial palsy. To define the evolution of the episode by tracing changes in facial function over time.
Methods: This is an observational prospective study on patients with facial palsy consulting in the first 24 hs.
Perforator plus supraclavicular flap for reconstruction following resection of extensive recurrent basal cell carcinoma of face: a case report.
J Surg Case Rep
January 2025
Department of Surgery, Armed Forces Medical College, Pune, Maharashtra, 411040, India.
Basal cell carcinomas are common facial malignancies with minimally invasive treatment approaches effective in the majority of cases. Recurrent aggressive lesions pose significant challenges and need wide local excision with major reconstruction. Geriatric patient with multiple comorbidities needs customized reconstructions to minimize morbidity.
View Article and Find Full Text PDFA OHCs-Targeted Strategy for PEDF Delivery in Noise-Induced Hearing Loss.
Adv Healthc Mater
January 2025
Department of Otorhinolaryngology-Head and Neck Surgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, 221002, P. R. China.
Noise-induced hearing loss (NIHL) results from prolonged exposure to intense noise, causing damage to sensory outer hair cells (OHCs) and spiral ganglion neurons (SGNs). The blood labyrinth barrier (BLB) hinders systemic drug delivery to the inner ear. This study applied a retro-auricular round window membrane (RWM) method to bypass the BLB, enabling the transport of macromolecular proteins into the inner ear.
View Article and Find Full Text PDFCutaneous dysbiosis characterizes the post-allogeneic hematopoietic stem cell transplantation period.
Blood Adv
January 2025
The Jackson Laboratory, United States.
Gut dysbiosis is linked to mortality and the development of graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT), but the impact of cutaneous dysbiosis remains unexplored. We performed a pilot observational study and obtained retroauricular and forearm skin swabs from 12 adult patients prior to conditioning chemotherapy/radiation, and at 1-week, 1-month and 3-months after allogeneic HSCT, and performed shotgun metagenomic sequencing. The cutaneous microbiome among HSCT patients was enriched for gram-negative bacteria such as E coli and Pseudomonas, fungi, and viruses.
View Article and Find Full Text PDFBone wax usage onto combined dorsal auricular areas: Posterior pinna and retroauricular sulcus. A series of six dermatological surgical cases.
JAAD Case Rep
November 2024
Dermatology Department, Hospital Mutua de Terrassa, Terrassa, Barcelona, Spain.
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