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Front Aging
December 2022
Dipartimento di Medicina, Chirurgia e Farmacia, University of Sassari, Sassari, Italy.
Villages in the island of Sardinia in the Mediterranean that display exceptional longevity are clustered within a defined mountainous region. Because of their unique location we hypothesize that these villages had a unique infectious disease exposure relevant to the observed successful longevity. These highland villages had a significant exposure to malaria in the first half of the 20th century after which malaria was eliminated due to vector control mechanisms.
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