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Efficacy and safety of diclofenac suppository for postoperative pain relief after diagnostic hystero-laparoscopy and dye test: A double-blind, placebo-controlled, randomized trial.
Eur J Obstet Gynecol Reprod Biol X
September 2024
Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria.
Article Synopsis
- The study aimed to assess the effectiveness and safety of rectal diclofenac for managing postoperative pain in women undergoing diagnostic hystero-laparoscopy and dye test.
- In a double-blind, placebo-controlled trial with 108 participants, pain levels were measured at various time points, showing diclofenac provided slightly lower pain scores but not significantly better than the placebo.
- Overall, while rectal diclofenac was deemed safe, it did not substantially enhance pain relief or patient satisfaction when compared to placebo treatments following surgery.
A randomized controlled trial of rectal versus intramuscular diclofenac for post-operative analgesia after open myomectomy.
Eur J Obstet Gynecol Reprod Biol
January 2024
Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University Teaching Hospital, Nnewi, Anambra State, Nigeria. Electronic address:
Aim: To determine the efficacy and safety of rectal versus intramuscularly administered Diclofenac in reducing post-operative pain in the first 24 h after open-myomectomy.
Methods: A single blind, placebo controlled randomized trial consisting of 90 consenting women that had open-abdominal-myomectomy. They were randomized into two-groups (rectal-group and intramuscular-group) of 45 women (1:1 ratio).
Effect of scalp infiltration with bupivacaine on analgesic requirement following elective craniotomy.
Ann Afr Med
November 2022
Department of Anaesthesiology and Intensive Care, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.
Background: Postcraniotomy pain and perioperative assessment of patients' neurological function are some of the issues associated with craniotomy surgeries. Cost-effective pain control will result in good clinical outcome, decrease the length of hospital stay, and reduce total cost. Infiltration anesthesia is a recognized modality of cost-effective pain control.
View Article and Find Full Text PDFSafety and efficacy of pentazocine-midazolam combination for pain and anxiety relief in radiofrequency ablation therapy for hepatocellular carcinoma.
JGH Open
August 2022
Division of Gastroenterology and Hepatology, Department of Internal Medicine The Jikei University School of Medicine Tokyo Japan.
Background And Aim: Radiofrequency ablation (RFA) therapy is frequently used as first-line treatment for small hepatocellular carcinoma (HCC). RFA is often associated with pain; however, no definitive solution has been established for its relief. We retrospectively analyzed the safety and efficacy of the combination of pentazocine and midazolam to relieve pain experienced by HCC patients undergoing RFA.
View Article and Find Full Text PDFAnalgesic efficacy and safety of paracervical block versus conscious sedation in the surgical evacuation of the uterus following first-trimester incomplete miscarriages: A randomised controlled trial.
SAGE Open Med
July 2022
Department of Obstetrics and Gynaecology, Alex Ekwueme Federal University Teaching Hospital Abakaliki, Abakaliki, Nigeria.
Objective: To compare the analgesic efficacy and safety of paracervical block and conscious sedation in the surgical evacuation of the uterus following a first-trimester miscarriage.
Methods: This is an open-label, randomised control trial comparing pain relief by paracervical block versus conscious sedation during manual vacuum aspiration of first-trimester incomplete miscarriages. One-hundred and sixty-two women were equally randomised into two groups.
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