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Pyometra alters uterine aquaporins related with lipopolysaccharide concentrations and antioxidant enzyme activities in bitches.

Anim Reprod Sci

December 2024

Ankara University, Faculty of Veterinary Medicine, Department of Obstetrics and Gynecology, Ankara 06110, Turkiye. Electronic address:

Article Synopsis
  • Pyometra is a serious inflammatory disease affecting older intact female dogs, particularly during the diestrus stage, and can lead to significant health issues.
  • The study examined five types of aquaporins (proteins that help transport water) in uterine tissue and their links to various health markers like blood lipopolysaccharide levels and antioxidant activity in dogs with pyometra.
  • Results showed changes in aquaporin levels between affected dogs and control dogs, including downregulation of AQP1, AQP2, and AQP5, while AQP9 and AQP3 were upregulated, suggesting a complex relationship between these proteins and the disease's progression.
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  • - Diarrhea in lambs, a critical health issue in ovine medicine, leads to substantial economic losses due to high mortality rates and treatment costs, with Salmonella and enterotoxigenic E. coli as primary causes.
  • - The study aimed to analyze genetic variations, gene expression, and biomarkers related to inflammation and oxidative stress in lambs with diarrhea, alongside identifying different strains of the pathogens involved.
  • - Results indicated the presence of specific virulence genes associated with E. coli and Salmonella in all diarrheic lambs, as well as identified genetic markers related to immune response, antioxidant activity, and gastrointestinal health.
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  • * Methodology: Thirty-six patients with single-rooted, necrotic teeth were treated, with bacteriological samples taken before and after applying the intracanal medicaments. Samples were cultured to count bacteria before and after treatment.
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Prognostic risk factors for pyogenic liver abscess caused by Klebsiella pneumoniae.

BMC Gastroenterol

September 2024

Department of Hepatobiliary Surgery, Dongyang People's Hospital, Affiliated Dongyang Hospital of Wenzhou Medical University, 60 West Wuning Road, Dongyang, Zhejiang, 322100, P.R. China.

Background: Pyogenic liver abscess (PLA) caused by Klebsiella pneumoniae can vary in severity, and several risk factors for the development of organ dysfunction in PLA have been implicated. However, few studies to date have explored the most common risk factors for clinical severity.

Methods: We conducted a study on patients with PLA caused by Klebsiella pneumoniae between February 2013 and December 2022.

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Objective: The following study examines for the first time the changes that occur in the post-partum period following abortion in the first trimester of dairy cows using hormonal, hematological, and oxidant/antioxidant profiles. In addition, a bacteriological examination was also performed to explore the role of infections in the complications that occur during this period.

Materials And Methods: One hundred cows were split into two equal groups: The first group enrolled cows that suffered from abortion in the first trimester.

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