Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1016/0014-4800(70)90088-2 | DOI Listing |
J Neurophysiol
January 2024
Department of Biological Sciences, University of Illinois at Chicago, Chicago, Illinois, United States.
Previous work has shown that activation of tiger salamander retinal radial glial cells by extracellular ATP induces a pronounced extracellular acidification, which has been proposed to be a potent modulator of neurotransmitter release. This study demonstrates that low micromolar concentrations of extracellular ATP similarly induce significant H effluxes from Müller cells isolated from the axolotl retina. Müller cells were enzymatically isolated from axolotl retina and H fluxes were measured from individual cells using self-referencing H-selective microelectrodes.
View Article and Find Full Text PDFTransl Vis Sci Technol
October 2023
The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong Province, China.
Purpose: This study aimed to establish a mouse model of chlorpromazine-induced corneal trigeminal denervation (CCTD).
Methods: Retrobulbar chlorpromazine injections were administered to 6- to 8-week-old C57BL/6j mice to induce corneal denervation. Additionally, apoptosis was assessed in isolated primary trigeminal ganglion cells after culturing in a conditioned medium containing chlorpromazine.
Int J Mol Sci
July 2023
Laboratory of Retinal Cell & Molecular Biology, National Eye Institute, National Institutes of Health, Bethesda, MD 20892, USA.
Biomolecules
September 2022
University Hospitals Eye Institute, Case Western Reserve University, Cleveland, OH 44101, USA.
It is important for clinicians to consider exposure to toxic substances and nutritional deficiencies when diagnosing and managing cases of vision loss. In these cases, physiologic damage can alter the function of key components of the visual pathway before morphologic changes can be detected by traditional imaging methods. Electrophysiologic tests can aid in the early detection of such functional changes to visual pathway components, including the retina or optic nerve.
View Article and Find Full Text PDFEur Arch Psychiatry Clin Neurosci
April 2023
Department of Psychiatry and Psychotherapy, University Hospital, LMU Munich, Nußbaumstraße 7, 80336, Munich, Germany.
Background: Schizophrenia spectrum disorders (SSDs) are presumed to be associated with retinal thinning. However, evidence is lacking as to whether these retinal alterations reflect a disease-specific process or are rather a consequence of comorbid diseases or concomitant microvascular impairment.
Methods: The study included 126 eyes of 65 patients with SSDs and 143 eyes of 72 healthy controls.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!