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Comparison of Apixaban and Aspirin in Preventing Portal Vein Thrombosis after Laparoscopic Splenectomy for Cirrhotic Hypersplenism.
Thromb Haemost
December 2024
Department of Hepatobiliary Surgery, Northern Jiangsu People's Hospital, Yangzhou, China.
Background: Portal vein system thrombosis (PVST) is a frequent and possibly fatal concurrent disorder following splenectomy. The optimal anticoagulant to prevent PVST following splenectomy remains unclear.
Objectives: The purpose of this study was to compare the safety and efficacy of apixaban versus aspirin in preventing PVST after laparoscopic splenectomy (LS) for cirrhotic hypersplenism.
A rare case of idiopathic portal hypertension with portopulmonary hypertension occurred following splenectomy with a change in portal hemodynamics.
Clin J Gastroenterol
December 2024
Department of Gastroenterology and Hepatology, Mie University Graduate School of Medicine, 2-174 Edobashi, Tsu, 514-8507, Japan.
Article Synopsis
- * She had a splenectomy to address her thrombocytopenia caused by an enlarged spleen (hypersplenism), but nine months later, she experienced exertional dyspnea and was diagnosed with portopulmonary hypertension (PoPH).
- * Treatment with the medication macitentan improved her symptoms and right heart pressure readings, marking a rare case of PoPH arising after splenectomy.
Laparoscopic Splenectomy with Pericardial Devascularization for Hypersplenism and Esophageal Variceal Hemorrhage Due to Portal Hypertension.
J Vis Exp
November 2024
Department of Hepatobiliary Surgery, The First Affiliated Hospital, Jinan University;
Article Synopsis
- Hypersplenism and esophageal variceal hemorrhage are serious complications of decompensated cirrhosis caused by portal hypertension.
- Although various non-surgical treatments have emerged, surgical options like splenectomy combined with pericardial devascularization (SPD) remain crucial in China for treating these conditions.
- The article emphasizes the effectiveness of laparoscopic splenectomy combined with pericardial devascularization (LSPD) as a minimally invasive surgical technique, highlighting the importance of surgeon skill for successful outcomes.
Clinical benefits of partial splenic embolization for cancer patients.
Hepatol Res
November 2024
Department of Gastroenterological Surgery, Graduate School of Life Sciences, Kumamoto University, Kumamoto, Japan.
Partial splenic embolization (PSE) has developed as an alternative to surgical splenectomy, mainly to improve hypersplenism and esophagogastric varices in cirrhotic patients. We proposed the novel concept that splenic infarction volume, rather than the splenic infarction ratio, is essential for patients receiving PSE. A splenic infarction volume between 388 and 540 mL is suitable for a sufficient increase in platelet count and less severe PSE-related complications.
View Article and Find Full Text PDFLeft-sided portal hypertension: what an interventional radiologist can offer?
Eur Radiol
November 2024
Department of Radiodiagnosis, All India Institute of Medical Sciences, Bhubaneswar, 751019, India.
Left-sided portal hypertension (LPH) refers to increased splenic venous pressure caused by splenic vein stenosis or occlusion. Pancreatitis is the leading cause of LPH. Typically, LPH remains asymptomatic, but it can lead to life-threatening hemorrhage from ruptured fundal varices in about 10% of patients.
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