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Influence of macrophages and neutrophilic granulocyte-like cells on crystalline silica-induced toxicity in human lung epithelial cells.
Toxicol Res (Camb)
February 2025
Département Toxicologie et Biométrologie, Institut National de Recherche et de Sécurité pour la prévention des accidents du travail et des maladies professionnelles (INRS), 1 rue du Morvan, 54519 Vandœuvre-lès-Nancy, France.
In many industrial activities, workers may be exposed by inhalation to particles that are aerosolized, To predict the human health hazard of these materials, we propose to develop a co-culture model (macrophages, granulocytes, and alveolar epithelial cells) designed to be more representative of the inflammatory pulmonary response occurring in vivo. Phorbol 12-myristate 13-acetate (PMA)-differentiated THP-1 cells were used as macrophages, All-trans retinoic acid (ATRA)-differentiated HL60 were used as granulocytes and A549 were used as epithelial alveolar type II cells. A crystalline silica sample DQ12 was used as a prototypical particle for its capabilities to induce DNA damage, inflammatory response, and oxidative stress in epithelial cells; its polyvinylpyridine-N-oxide (PVNO)-surface modified counterpart was also used as a negative particulate control.
View Article and Find Full Text PDFMachine vision model for drip leakage detection of pipeline.
PLoS One
January 2025
School of Power and Mechanical Engineering, Wuhan University, Wuhan, China.
The prevailing trend in industrial equipment development is integration, with pipelines as the lifeline connecting system components. Given the often harsh conditions of these industrial equipment pipelines, leakage is a common occurrence that can disrupt normal operations and, in severe cases, lead to safety accidents. Early detection of even minor drips at the onset of leakage can enable timely maintenance measures, preventing more significant leaks and halting the escalation of pipeline failures.
View Article and Find Full Text PDFOccupational Injuries and Fatalities in Norwegian Fish Farming.
J Agromedicine
January 2025
Department of Fishery and New Biomarine Industry, SINTEF Ocean, Trondheim, Norway.
Objective: People working in the Norwegian fish farming industry work in a high energy environment, where there are many hazards in the daily work. An important part of mitigating hazardous situations is to keep track of the characteristics of the accidents that have already happened and to learn from these, when planning future work. The objective of this study was to strengthen the knowledge of factors and conditions influencing personnel safety in Norwegian fish farming, based on analyses of registered occupational fatalities and injuries.
View Article and Find Full Text PDF[Not Available].
Tunis Med
January 2025
Department of Ophthalmology, Habib Bourguiba Hospital, Sfax Faculty of Medicine, University of Sfax, Tunisia.
Introduction: Work-related open-globe injuries are a major cause of preventable vision loss worldwide with a significant socioeconomic impact.
Aim: To describe the demographics and clinical characteristics, identify the prognostic factors of work-related open-globe injuries and suggest preventive measures to minimize the incidence of these accidents.
Methods: A retrospective study of patients hospitalized in the Ophthalmology Department of Habib Bourguiba University Hospital, Sfax, Tunisia, for occupational open-globe injuries, between January 2020 and December 2022.
Enhancing road safety of PLEVs by novel vehicle concepts: A comprehensive investigation on regulations, accident statistics, and perception of riders in Europe.
Heliyon
January 2025
Department of Industrial Engineering, Università degli Studi di Firenze, Via di Santa Marta, 3, 50139, Firenze, Italy.
The rise of Personal Light Electric Vehicles (PLEVs), including electric bicycles and electric kick scooters, represents a relevant trend in current urban mobility. PLEVs offer economic, social, and environmental advantages, making them increasingly attractive for short-distance travel. Despite their benefits, concerns about the safety of PLEVs, particularly related to road accidents, have arisen due to their growing presence in urban areas.
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