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Introduction Balanitis xerotica obliterans (BXO) can cause phimosis, meatal stenosis, and urethral strictures. However, management of these conditions in BXO patients is difficult. Surgical interventions, with their own risks and complications, demonstrate higher rates of disease recurrence.
View Article and Find Full Text PDFCurrent Potential Outcomes of Buccal Mucosal Graft Anterior Urethroplasty for Male Urethral Stricture: A Single-Centre Study in Nepal.
Cureus
September 2024
Urology, National Academy of Medical Sciences, Bir Hospital, Kathmandu, NPL.
Article Synopsis
- This study analyzes the effectiveness and complications of Buccal Mucosal Graft (BMG) urethroplasty for treating anterior urethral strictures in 130 patients over a 48-month period.
- The results show an 84.6% success rate, with recurrence occurring in 15.4% of cases and complications such as erectile dysfunction (11%) and post-micturition dribbling (14%) reported.
- Key factors predicting stricture recurrence include age, stricture length, and anatomical location, with penile location being the strongest predictor.
Down Syndrome in Children: A Primary Immunodeficiency with Immune Dysregulation.
Children (Basel)
October 2024
Student Scientific Society, English Division, Poznań University of Medical Sciences, 61-701 Poznań, Poland.
The multisystemic features of Down syndrome (DS) in children are accompanied by immunodeficiency, making them susceptible to infections and immune dysregulation with autoimmune, allergic, inflammatory, and hematological complications. This study was aimed at a better understanding of the abnormalities within the B and T cell compartments and their correlations with clinical immunophenotypes. Medical records of 35 DS children were retrospectively reviewed, referring to clinical symptomatology including history of infections, immune dysregulation disorders, and humoral and cellular immune response.
View Article and Find Full Text PDFArticle Synopsis
- * A case study involved a 32-year-old male who received Ayurvedic Uttar Basti therapy over nine months, which includes the administration of medicated oil through the urethra.
- * The treatment led to significant improvements in urinary flow metrics, including a 25% increase in Maximum Flow rate and a 143% increase in Average Flow rate, also allowing the patient to avoid further surgery.
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