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Treponema Pallidum: A Forgotten Pathogen With Major Cardiovascular Consequence.
JACC Case Rep
November 2024
Division of Cardiology, Department of Medicine, David Geffen School of Medicine, University of California-Los Angeles, Los Angeles, California, USA.
Article Synopsis
- The rate of syphilis cases has risen significantly over the past 20 years.
- This case study discusses a 43-year-old man who presented with an aortic aneurysm and aortic regurgitation, initially thought to be a congenital issue.
- Eventually, it was confirmed that the aortic problems were due to tertiary syphilis, highlighting the importance of considering syphilis as a potential cause of heart-related conditions.
Persistent hypoglycemia in congenital syphilis: hyperinsulinemic hypoglycemia with a focal pancreatic lesion.
J Pediatr Endocrinol Metab
January 2025
Department of Infectious Diseases, University of Health Sciences, Bursa Yuksek İhtisas Training and Research Hospital, Bursa, Türkiye.
Objectives: Congenital syphilis can cause severe morbidities such as hydrops fetalis, preterm birth, low birth weight, hepatosplenomegaly, pneumonia, hypoglycemia, etc., and mortality. Despite hypoglycemia being reported in congenital syphilis and hyperinsulinism, only one case was described.
View Article and Find Full Text PDFFetal and neonatal outcomes in syphilis infected pregnant women in Reunion Island: An observational retrospective multicentric study.
PLoS One
November 2024
Department of Gynecology and Obstetrics, University Hospital of La Réunion, Saint Pierre, Reunion Island, France.
Objectives: To evaluate the fetal and neonatal morbidity and mortality in pregnant women with syphilis during their pregnancy in Reunion Island, population benefiting from early and well-conducted screening and treatment.
Methods: This is a retrospective observational study conducted in the four Reunion hospital centers between 2017 and 2022. The included patients were all pregnant patients with a biologically proven syphilitic infection and having given birth in one of the four centers mentioned.
A Case of Syphilis Associated With Genital and Extragenital Hard Chancres, Inguinal Lymphadenitis, and Systemic Symptoms.
Cureus
October 2024
Department of Dermatology, Tokyo Metropolitan Police Hospital, Tokyo, JPN.
Syphilis is a sexually transmitted infection caused by the spirochete (TP) subspecies . Syphilis can be transmitted via contact with infected bodily fluids, such as blood or semen, congenital infection, blood transfusion, or organ transplantation. After a brief incubation period, the disease manifests with signs and symptoms such as genital ulcers, erythematous papules on the palms and soles, fever, and lymphadenopathy.
View Article and Find Full Text PDFA case of early-onset congenital syphilitic osteomyelitis of the calcaneus and literature review.
BMC Pediatr
October 2024
Department of Orthopaedic Surgery, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China.
Article Synopsis
- Congenital syphilis (CS) can lead to rare cases of calcaneal osteomyelitis in infants, as illustrated by a case involving a 4-month-old boy with swelling in his foot but no prior trauma.
- Imaging revealed bone loss in the calcaneus, and the infant had a history of CS diagnosed during an earlier hospitalization.
- Timely surgical intervention and antibiotic therapy were successful in healing the bone and restoring mobility, highlighting the importance of considering CS in cases of unexplained foot infections in infants.
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