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A Novel Approach of Ultrasound-Guided Transforaminal Cervical Nerve Root Injection With Fluoroscopic Validation: A Case Report and Technical Illustration.
Cureus
December 2024
Pain and Rehabilitation, Regen Clinic, Taipei, TWN.
Cervical radiculopathies are commonly treated with nerve root injections. This study presents a novel ultrasound (US)-guided cervical transforaminal injection technique using a curved transducer to enhance visualization of the anterior wall of the superior articular process and achieve successful epidural spread of injection. A 56-year-old patient with chronic C6 radiculopathy was treated using our US-guided approach with a combination of 5% dextrose and vitamin B12, leading to significant improvement in symptoms.
View Article and Find Full Text PDFOptimisation of Blood Donor Nutrition: Blood Donor Health Improvement Studies.
Cell Physiol Biochem
December 2024
Institute of Biology, Pomeranian University in Słupsk, Słupsk, Poland.
This review provides an analysis of the current literature on the health and nutrition of blood donors, examining key aspects that affect the quality of donated blood and the well-being of donors. The review discusses effective iron absorption facilitated by key nutrients and presents evidence on the importance of a balanced diet rich in essential nutrients, such as vitamin B12 and folic acid. The review examines the differences in iron levels between men and women and highlights the role of sex hormones in regulating iron metabolism.
View Article and Find Full Text PDFInvestigating the Impact of Selected B Vitamins (B1, B2, B6, and B12) on Acute Colitis Induced Experimentally in Rats.
Int J Prev Med
November 2024
Department of Pharmacology and Toxicology, School of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan, Iran.
Background: Malnutrition and lack of micronutrients are seen in many patients with ulcerative colitis (UC). Considering that vitamins play an important role in preventing or protecting against inflammation at the metabolic, physiological, and pathological levels, this research was aimed to investigate the effect of a number of vitamin B groups in improving UC.
Methods: Experimental colitis was induced by rectal administration of acetic acid (3%) in male Wistar rats, and mega doses of thiamine (20 mg/kg), riboflavin (15 mg/kg), pyridoxine (30 mg/kg), and cyanocobalamin (250 μg/kg) alone or in combination were administered intraperitoneally for 5 days.
Nitrous Oxide Causing Subacute Combined Degeneration: A Case Report.
Cureus
November 2024
Internal Medicine, Methodist Dallas Health System, Dallas, USA.
This case report describes a 31-year-old male who developed subacute combined degeneration as a result of vitamin B12 deficiency caused by recreational use of nitrous oxide ("whippets") over a six-month period. nitrous oxide, widely available and often used for its euphoric effects, can lead to alterations in B12 metabolism and decreased myelination, particularly in the dorsal columns, with prolonged use. Despite prompt diagnosis and treatment, including intramuscular B12 injections and physical therapy, he experienced residual weakness and required outpatient rehabilitation.
View Article and Find Full Text PDFElevated Vitamin B12 Levels in Myeloproliferative Neoplasm (MPN) Patients: A Potential Diagnostic and Prognostic Marker.
J Blood Med
December 2024
Department of Hematology, Hamad Medical Corporation, Doha, Qatar.
Background: Elevated vitamin B12 (B12) levels are linked to an increased risk of cancers, including hematological malignancies. This study focuses on the relationship between elevated B12 and myeloproliferative neoplasms (MPNs): Polycythemia Vera (PV), Primary Myelofibrosis (MF), Essential Thrombocytosis (ET), and Chronic Myeloid Leukemia (CML). Elevated B12 in MPNs is believed to arise from increased transcobalamin I (TCI) secretion by proliferating leukocytes, leading to higher serum levels.
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