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Left supraclavicular parathyroid carcinoma: diagnostic difficulties through a case report.
Pan Afr Med J
November 2024
Ear, Nose, and Throat, Head and Neck Surgery Department, Hospital of Specialties, Mohammed V University, Rabat, Morocco.
Parathyroid carcinoma is a very rare malignant tumour of the parathyroid gland, accounting for less than 0.005% of all cancers, and less than 1% of the aetiologies of primary hyperparathyroidism. This case report aims to describe the incidental discovery of a non-secreting parathyroid carcinoma in a left supraclavicular location and to report on the diagnostic difficulties encountered, together with a review of the literature and current management issues.
View Article and Find Full Text PDFAdrenal Schwannoma Presenting as an Incidentaloma in a Patient with Uterine Fibroids and Cholelithiasis: a Rare Case Report.
Indian J Surg Oncol
September 2024
Department of General Surgery, King George's Medical University, Shah Mina Shah Road, Chowk, Lucknow, 226003 Uttar Pradesh India.
Schwannomas, which are benign mesenchymal tumors derived from Schwann cells, are common in the central nervous system. While they are commonly seen in the extremities and head-neck area, their presence in visceral organs, particularly the adrenals, is uncommon. Adrenal schwannomas are frequently discovered incidentally, offering a diagnostic difficulty because of their uncommon presentation.
View Article and Find Full Text PDFPhenotypic presentation of c.758delC (p.Ser253Cys 28) pathogenic variant: a case report.
Oxf Med Case Reports
September 2024
Division of Anatomic Pathology and Histology, Catholic University of Sacred Heart, Largo Agostino Gemelli, 8, 00168, Rome, Italy.
Article Synopsis
- - A 32-year-old man with MEN1 syndrome presented with multiple health issues, including hyperparathyroidism, but no prolactin or growth hormone-secreting tumors were found.
- - After a subtotal parathyroidectomy, he was diagnosed with non-functioning pituitary adenoma, pancreatic lesions, and Cushing syndrome linked to an adrenal adenoma.
- - Genetic testing confirmed MEN1 syndrome, revealing a new pathogenic mutation (c.758delC) in the MEN1 gene.
A Non-Secreting Pituitary Adenoma That Changed to a Prolactinoma.
Clin Pract
July 2024
Servicio Endocrinología y Nutrición, Hospital Universitario A Coruña, 15006 A Coruña, Spain.
Pituitary adenomas (PAs) are the third most common brain tumors in adults right after meningiomas and gliomas. Taking into account their hormonal activity in vivo, they can be divided in functioning PAs, which secrete hormones, and nonfunctioning pituitary adenomas (NFPAs), which are not associated with increased hormone secretion. We present the case of a man diagnosed with pituitary apoplexy.
View Article and Find Full Text PDFFrom Adenoma to Carcinoma: the Unexpected Evolution of an Apparently Stable Adrenal Lesion.
Endocr Metab Immune Disord Drug Targets
July 2024
Endocrine Unit, ASST Grande Ospedale Metropolitano Niguarda, Piazza Ospedale Maggiore 3, 20162, Milan, Italy.
Article Synopsis
- A 75-year-old man had a small adrenal mass that looked harmless during tests for two years.
- Later, it was found to have grown much bigger and was diagnosed as adrenal cancer.
- The case shows that even if a mass seems stable, it should still be checked regularly, as it can become dangerous.
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